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[脊髓损伤/疾病患者神经泌尿护理的重要性]

[Importance of neuro-urological care in patients with spinal cord injuries/diseases].

作者信息

Wöllner Jens, Kurze Ines

机构信息

Schweizer Paraplegiker Zentrum, Nottwil, Schweiz.

Klinik für Paraplegiologie und Neuro-Urologie, Zentralklinik Bad Berka Gmbh, Bad Berka, Germany.

出版信息

Aktuelle Urol. 2024 Aug;55(4):308-314. doi: 10.1055/a-2252-0323. Epub 2024 Jun 27.

Abstract

Integrity, control and regulation of the urinary tract are subject to a complex neuronal regulation, in which portions of the sympathetic, parasympathetic and somatic nervous system are involved. The spinal cord plays a central role in regulation and serves as a transmitter for the motor and sensory pathways. Bladder dysfunction followed by renal dysfunction was the most frequent cause of death in patients with spinal cord injuries/diseases (paraplegia) as recently as half a decade ago. Thanks mainly to diagnostic and therapeutic advances made in neuro-urology, urological problems are no longer life-limiting. A vital role is played not only by the actual function of the urinary tract but also by the complex interactions in patients living with paraplegia. Issues such undertreated hyperactivity of the detrusor muscle with autonomous dysregulation, incontinence with secondary skin changes, or insufficient hand function to perform intermittent catheterisation must be evaluated in an interdisciplinary approach. Spinal cord injury/disease implies numerous functional disorders and secondary impairments of the organism. In addition to bladder function, sexual dysfunction also plays a crucial role. Especially in younger patients who sustain paraplegia before or during the family planning phase, this disruption and limitation is an essential reason for reduced quality of life. Neurogenic intestinal function plays an additional crucial role with regard to quality of life and management of everyday life. In recent years, the range of neuro-urological topics has expanded significantly. The focus of our work shifted from being merely on the urinary tract and urodynamics. In particular, the diagnostic investigation and treatment of neurogenic intestinal dysfunction is increasingly in the hands of neuro-urologists. The complex presentation of paraplegia involves an interaction of bladder, intestinal and sexual dysfunction in a way that these influence one another. Therefore, the sustained care and re-integration of these patients essentially includes lifelong and regular neuro-urological care in a paraplegia centre. Last but not least, it is exactly these neuro-urological topics such as urinary tract infections, urinary and intestinal incontinence and faecal impaction, which most commonly lead to re-hospitalisation.

摘要

尿路的完整性、控制和调节受复杂的神经调节,交感神经、副交感神经和躯体神经系统的部分均参与其中。脊髓在调节中起核心作用,是运动和感觉通路的传导者。就在仅仅五年前,膀胱功能障碍继而导致肾功能障碍还是脊髓损伤/疾病(截瘫)患者最常见的死亡原因。主要得益于神经泌尿学在诊断和治疗方面的进展,泌尿系统问题已不再危及生命。不仅尿路的实际功能,而且截瘫患者体内复杂的相互作用都起着至关重要的作用。对于逼尿肌自主调节功能亢进治疗不足、失禁伴继发性皮肤改变或手功能不足以进行间歇性导尿等问题,必须采用多学科方法进行评估。脊髓损伤/疾病意味着机体出现众多功能障碍和继发性损害。除膀胱功能外,性功能障碍也起着关键作用。特别是在计划生育阶段之前或期间发生截瘫的年轻患者中,这种功能紊乱和限制是生活质量下降的重要原因。神经源性肠道功能在生活质量和日常生活管理方面也起着额外的关键作用。近年来,神经泌尿学的主题范围显著扩大。我们的工作重点已从仅仅关注尿路和尿动力学转移。特别是,神经源性肠道功能障碍的诊断研究和治疗越来越多地由神经泌尿学家负责。截瘫的复杂表现涉及膀胱、肠道和性功能障碍的相互作用,这些功能相互影响。因此,对这些患者的持续护理和重新融入社会基本上包括在截瘫中心进行终身定期的神经泌尿学护理。最后但同样重要的是,正是这些神经泌尿学问题,如尿路感染、尿失禁和大便失禁以及粪便嵌塞,最常导致再次住院。

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