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黄杨属的药理学和植物化学特性:综述。

Pharmacological and phytochemical properties of the genus Buxus: A review.

机构信息

Team of Ethnopharmacology and Pharmacognosy, Faculty of Sciences and Techniques Errachidia, Moulay Ismail University of Meknes, BP 509, Boutalamine, Errachidia 52000, Morocco; Energy, materials and sustainable development (EMDD) Team- Higher School of Technology-SALE, Center for Water, Natural Resources Environment and Sustainable Development (CERNE2D), Mohammed V University in Rabat, Rabat, Morocco.

Team of Ethnopharmacology and Pharmacognosy, Faculty of Sciences and Techniques Errachidia, Moulay Ismail University of Meknes, BP 509, Boutalamine, Errachidia 52000, Morocco.

出版信息

Fitoterapia. 2024 Sep;177:106081. doi: 10.1016/j.fitote.2024.106081. Epub 2024 Jun 25.

DOI:10.1016/j.fitote.2024.106081
PMID:38936673
Abstract

BACKGROUND

Buxus plants have been used in traditional medicine for a very long time. The Buxus genus has been used to cure a variety of illnesses.

OBJECTIVE

This review aimed to provide a literature review on the genus Buxus including its biological and phytochemical properties.

MATERIALS AND METHODS

The current study was conducted using several scientific databases. Correct plant names were verified from plantlist.org. The results of this search were interpreted, analyzed, and documented based on the obtained bibliographic information.

RESULTS

Within all the species of the family Buxaceae, 5 species of the genus Buxus are reported to be antibacterial, 3 species have been found to be antioxidant, 5 species are cytotoxic, 1 species is anti-inflammatory, 1 species is antidiabetic, and 4 species are antifungal. Alkaloids, terpenoids, tannins, flavonoids, peptides, and phenolic compounds are the main chemical components of this genus. The study of >11 Buxuss pecies has identified >201 compounds. Pharmacological research has demonstrated that crude extracts and some pure compounds obtained from Buxus have several pharmacological activities such as antibacterial, antioxidant, cytotoxic, anti-inflammatory, antidiabetic, and antifungal. Based on the study of the phytochemistry of Buxus species, it was concluded that all the studied plants have active compounds, among which 55 molecules showed interesting activities.

CONCLUSIONS

The numerous traditional uses of Buxus species have been supported by several studies. Before Buxus plants can be fully employed clinically, further research is necessary.

摘要

背景

黄杨属植物在传统医学中应用已久,该属植物已被用于治疗多种疾病。

目的

本综述旨在提供黄杨属植物的文献综述,包括其生物学和植物化学特性。

材料和方法

本研究使用了多个科学数据库。通过 plantlist.org 验证了正确的植物名称。根据获得的文献信息,对该搜索的结果进行了解释、分析和记录。

结果

在黄杨科的所有种中,有 5 种被报道具有抗菌作用,3 种具有抗氧化作用,5 种具有细胞毒性,1 种具有抗炎作用,1 种具有抗糖尿病作用,4 种具有抗真菌作用。生物碱、萜类、单宁、类黄酮、肽和酚类化合物是该属的主要化学成分。对 >11 种黄杨属植物的研究已经鉴定出 >201 种化合物。药理学研究表明,黄杨属植物的粗提取物和一些纯化合物具有多种药理活性,如抗菌、抗氧化、细胞毒性、抗炎、抗糖尿病和抗真菌。基于对黄杨属植物的植物化学研究,可以得出结论,所有研究的植物都含有活性化合物,其中 55 种分子表现出有趣的活性。

结论

黄杨属植物的许多传统用途得到了多项研究的支持。在黄杨属植物能够充分应用于临床之前,还需要进一步研究。

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