Paediatric Respiratory, King's College Hospital NHS Foundation Trust, London, UK
Paediatric Radiology, Royal Brompton Hospital, London, UK.
BMJ Case Rep. 2024 Jun 27;17(6):e261171. doi: 10.1136/bcr-2024-261171.
In this paper, we report the case of a boy in early childhood who presented with iron-deficiency anaemia, initially thought to be nutritional, who had a subsequent diagnosis of idiopathic pulmonary haemosiderosis (IPH). This is a slowly progressive and life-threatening disorder and is of paramount importance that this is identified early and treated appropriately. His first chest CT was not typical for IPH, and this appearance should be highlighted (small cystic changes alone initially). He also had focal disease, which allowed us to make the diagnosis using CT-guided biopsy. During his treatment, he experienced an uncommon side effect to a commonly prescribed medication (bradycardia with methylprednisolone). Since starting azathioprine as a steroid-sparing agent, he has been doing well.
本文报道了一例早期儿童病例,该患儿最初表现为缺铁性贫血,被认为是营养性的,随后被诊断为特发性肺含铁血黄素沉着症(IPH)。这是一种进展缓慢且危及生命的疾病,早期识别和适当治疗至关重要。他的第一次胸部 CT 对 IPH 不典型,这种表现应该被强调(最初仅为小囊状改变)。他还患有局灶性疾病,这使我们能够通过 CT 引导下的活检做出诊断。在治疗过程中,他出现了一种常见药物(甲泼尼龙引起的心动过缓)的罕见副作用。自从开始使用硫唑嘌呤作为类固醇保存剂以来,他的病情一直很好。