Miranda Stefani, Harahap Aminuddin, Husada Dominicus, Faramarisa Fara Nayo
Department of Child Health Faculty of Medicine Hang Tuah University/dr. Ramelan Navy Central Hospital, Jalan Gadung No. 1, Surabaya, East Java 60244, Indonesia.
Department of Child Health dr. Ramelan Navy Central Hospital, Jalan Gadung No. 1, Surabaya East Java 60244, Indonesia.
Int J Pediatr. 2024 May 28;2024:6264980. doi: 10.1155/2024/6264980. eCollection 2024.
The morbidity and mortality rates from neonatal sepsis remain high. However, there is limited information about the microbial pattern of neonatal sepsis in Indonesia. Microbial patterns can give an overview of the hygiene of an environment and act as a determinant for choosing definitive antibiotic treatment in neonatal sepsis patients. The organisms that cause neonatal sepsis differ from unit to unit and from time to time within the same unit.
This study is aimed at discovering the microbial pattern of neonatal sepsis in the Neonatal Intensive Care Unit (NICU), dr. Ramelan Navy Central Hospital, in 2021-2022.
This is a retrospective, cross-sectional study that takes secondary data from the NICU and clinical microbiology department of dr. Ramelan Navy Central Hospital. Data that met the inclusion and exclusion criteria available between January 1, 2021, and December 31, 2022, were collected. Patients whose blood cultures were positive for bacterial growth and diagnosed with sepsis were selected as the study sample.
Out of 174 samples, 93 (53.4%) were found positive for bacterial infection and diagnosed as neonatal sepsis. Gram-negative isolates (96.8%) were predominant. Sixty-point-two percent of , 19.4% of , and 8.6% of were identified. The gram-positive isolates found in this study were only 3 samples (3.2%). Two-point-one percent of and 1.1% of were identified.
The most common microorganisms causing neonatal sepsis in our NICU were gram-negative bacteria, particularly . Following the recommended infection control procedures, practicing good hand hygiene, and having access to basic supplies and equipment are important to prevent and reduce the incidence of sepsis.
新生儿败血症的发病率和死亡率仍然很高。然而，关于印度尼西亚新生儿败血症的微生物模式的信息有限。微生物模式可以概述一个环境的卫生状况，并作为选择新生儿败血症患者确定性抗生素治疗的决定因素。引起新生儿败血症的病原体在不同单位之间以及同一单位的不同时间有所不同。
本研究旨在发现2021 - 2022年在拉梅兰海军中央医院新生儿重症监护病房（NICU）中新生儿败血症的微生物模式。
这是一项回顾性横断面研究，从拉梅兰海军中央医院的新生儿重症监护病房和临床微生物学部门获取二手数据。收集了2021年1月1日至2022年12月31日期间符合纳入和排除标准的数据。血液培养细菌生长呈阳性且被诊断为败血症的患者被选为研究样本。
在174个样本中，93个（53.4%）被发现细菌感染呈阳性，并被诊断为新生儿败血症。革兰氏阴性菌分离株（96.8%）占主导。鉴定出60.2%的[具体细菌名称未给出]、19.4%的[具体细菌名称未给出]和8.6%的[具体细菌名称未给出]。本研究中发现的革兰氏阳性菌分离株仅有3个样本（3.2%）。鉴定出2.1%的[具体细菌名称未给出]和1.1%的[具体细菌名称未给出]。
在我们的新生儿重症监护病房中，引起新生儿败血症最常见的微生物是革兰氏阴性菌，尤其是[具体细菌名称未给出]。遵循推荐的感染控制程序、保持良好的手部卫生以及具备基本的用品和设备对于预防和降低败血症的发病率很重要。
