Gerkowicz Agnieszka, Bartosińska Joanna, Krakowski Przemysław, Karpiński Robert, Krasowska Danuta, Raczkiewicz Dorota, Kwasny Mirosław, Krasowska Dorota
Department of Dermatology, Venereology and Paediatric Dermatology, Medical University, Lublin, Poland.
Department of Cosmetology and Aesthetic Medicine, Medical University, Lublin, Poland.
Ann Agric Environ Med. 2024 Jun 27;31(2):239-247. doi: 10.26444/aaem/177238. Epub 2024 Jan 8.
Photobiomodulation with the use of light-emitting diodes (LEDs) seems to be a promising option for long COVID. This retrospective study evaluates the efficiency of LED irradiation in the treatment of TE in the course of long COVID in patients with and without androgenetic alopecia.
A retrospective single-centre chart review of patients with post-COVID hair loss was performed. 140 patients enrolled to the study were divided into four groups depending on the type of alopecia and treatment: 1) telogen effluvium with LED therapy (TE LED+), 2) telogen effluvium without LED therapy (TE LED-), 3) telogen effluvium and androgenetic alopecia with LED therapy (TE+AGA LED+), and 4) telogen effluvium and androgenetic alopecia without LED therapy (TE+AGA LED-). Clinical and trichoscopic parameters were compared.
After 12 weeks, cessation of hair loss and a negative hair pull test were more common in TE LED+ and TE+AGA LED+ in comparison to the patients without LED therapy (p<0.001, p=0.035, respectively). An increased number of thick hairs and an increased number of hairs within follicular units were more common in patients treated with LED irradiation, regardless of the type of alopecia, compared to the patients without LED therapy.
The study revealed that LED therapy is safe, well tolerated and seems to be a promising therapeutic option for TE in patients with long COVID. It can be used as adjuvant therapy leading to faster reduction of hair loss, enhancing hair regrowth as well as hair shaft thickness and density.
使用发光二极管（LED）进行光生物调节似乎是治疗长期新冠后遗症的一个有前景的选择。这项回顾性研究评估了LED照射对患有和未患有雄激素性脱发的长期新冠患者治疗休止期脱发（TE）的疗效。
对新冠后脱发患者进行了一项回顾性单中心病历审查。根据脱发类型和治疗方法，将纳入研究的140名患者分为四组：1）接受LED治疗的休止期脱发（TE LED+），2）未接受LED治疗的休止期脱发（TE LED-），3）接受LED治疗的休止期脱发合并雄激素性脱发（TE+AGA LED+），4）未接受LED治疗的休止期脱发合并雄激素性脱发（TE+AGA LED-）。比较了临床和毛囊镜检查参数。
12周后，与未接受LED治疗的患者相比，TE LED+组和TE+AGA LED+组脱发停止且拔发试验呈阴性更为常见（分别为p<0.001，p=0.035）。与未接受LED治疗的患者相比，无论脱发类型如何，接受LED照射治疗的患者中粗发数量增加和毛囊单位内毛发数量增加更为常见。
该研究表明，LED治疗安全、耐受性良好，似乎是长期新冠患者TE的一种有前景的治疗选择。它可作为辅助治疗，导致脱发更快减少，促进头发生长以及毛干厚度和密度增加。
