Department of Otolaryngology, Tohoku Kosai Hospital, 2-3-11 Kokubun-cho, Aoba-ku, Sendai, 980-0803, Japan.
Department of Otolaryngology, Head and Neck Surgery, Tohoku University School of Medicine, 1-1 Seiryo-Machi, Aoba-ku, Sendai, 980-8574, Japan.
Eur Arch Otorhinolaryngol. 2024 Nov;281(11):5801-5806. doi: 10.1007/s00405-024-08803-w. Epub 2024 Jun 28.
In Japan, two types of tests for diagnosing olfactory disorders, T and T (T&T) olfactometry and intravenous olfactory tests, are covered by insurance and performed on patients with olfactory disorders. This study examined the validity of these olfactory tests and whether psychophysical or morphological tests are more helpful in evaluating olfactory disorders.
We evaluated patients who visited our department and underwent two types of olfaction tests and sinus computed tomography (CT). Data regarding the age, sex, peripheral blood eosinophil percentage, presence of bronchial asthma, diagnoses, olfactory symptom score, results of the two olfactory tests, and CT findings in eligible patients were extracted from medical records and retrospectively reviewed.
One hundred and sixty-three patients underwent all tests during the study period. The results of the T&T olfactometry and intravenous olfactory tests were significantly correlated. However, only the results of T&T olfactometry and olfactory cleft opacification on CT were statistically significant predictors of the olfactory symptom scores.
T&T olfactometry and CT evaluations of olfactory cleft opacification helped evaluate olfactory dysfunction. It is important to note that intravenous olfactory tests are best performed with careful control and not blindly to assess olfactory disorders.
在日本，有两种用于诊断嗅觉障碍的测试方法，即 T&T 嗅觉测试和静脉内嗅觉测试，这两种方法都可通过保险报销，并应用于嗅觉障碍患者。本研究旨在检验这些嗅觉测试的有效性，以及心理物理学或形态学测试在评估嗅觉障碍方面是否更有帮助。
我们评估了来我院就诊并接受两种嗅觉测试和鼻窦计算机断层扫描（CT）的患者。从病历中提取符合条件的患者的年龄、性别、外周血嗜酸性粒细胞百分比、支气管哮喘的存在、诊断、嗅觉症状评分、两种嗅觉测试的结果以及 CT 发现的数据，并进行回顾性分析。
在研究期间，163 名患者接受了所有测试。T&T 嗅觉测试和静脉内嗅觉测试的结果显著相关。然而，只有 T&T 嗅觉测试和 CT 嗅裂混浊的结果是嗅觉症状评分的统计学显著预测因素。
T&T 嗅觉测试和 CT 评估嗅裂混浊有助于评估嗅觉功能障碍。需要注意的是，静脉内嗅觉测试最好在仔细控制的情况下进行，而不是盲目进行，以评估嗅觉障碍。
