不同病因嗅觉功能障碍的MRI相关性及与主观和客观嗅觉测量法的比较
Correlation of olfactory dysfunction of different etiologies in MRI and comparison with subjective and objective olfactometry.
作者信息
Goektas Oender, Fleiner Franca, Sedlmaier Benedikt, Bauknecht Christian
机构信息
Department of Otolaryngology-Head and Neck Surgery, University of Berlin, Charité Campus Mitte, Smell and Taste Consultation Service, Berlin, Germany.
出版信息
Eur J Radiol. 2009 Sep;71(3):469-73. doi: 10.1016/j.ejrad.2008.10.039. Epub 2008 Dec 13.
BACKGROUND
The clinical diagnosis of olfactory dysfunction of different etiologies has been standardized by the German Working Group of Olfactology and Gustology, but there is no agreement about the most suitable imaging modality for diagnosing this disorder.
MATERIAL AND METHODS
A total of 24 patients (13 women, 11 men; mean age 52 years) with different types of olfactory dysfunction (anosmia, hyposmia) were examined by objective and subjective olfactometry and magnetic resonance imaging (MRI) of the olfactory bulb.
RESULTS
There was a positive correlation between objective olfactometry and volumetry of the olfactory bulb but no correlation between subjective olfactometry and MRI.
CONCLUSION
MRI allows an evaluation of the olfactory bulb and appears to be superior to other modalities such as computed tomography (CT). Objective olfactometry remains the gold standard for reliable diagnosis of olfactory dysfunction.
背景
德国嗅觉与味觉学工作组已对不同病因的嗅觉功能障碍的临床诊断进行了标准化，但对于诊断该疾病最合适的成像方式尚无共识。
材料与方法
对24例不同类型嗅觉功能障碍（嗅觉丧失、嗅觉减退）患者（13名女性，11名男性；平均年龄52岁）进行了客观和主观嗅觉测量以及嗅球磁共振成像（MRI）检查。
结果
客观嗅觉测量与嗅球容积测量之间存在正相关，但主观嗅觉测量与MRI之间无相关性。
结论
MRI可对嗅球进行评估，似乎优于其他成像方式，如计算机断层扫描（CT）。客观嗅觉测量仍然是可靠诊断嗅觉功能障碍的金标准。
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