Suppr超能文献

三维打印导航模板用于猪模型和患者经皮肾穿刺精准治疗肾积脓:病例报告

Three-dimensional printing the navigation template for precise percutaneous renal puncture to treat pyonephrosis on a porcine model and a patient :a case report.

作者信息

Kaile Zhang, Jiafu Liu, Wenyao Li, Xi Yang, Ding Li, Rong Chen, Qiang Fu

机构信息

The Department of Urology, Affiliated Sixth People's Hospital, Shanghai Jiao tong University school of medicine, Shanghai, 200233, China.

School of Material Engineering, Shanghai University of Engineering Science, Shanghai, 201620, China.

出版信息

Heliyon. 2024 Jun 4;10(11):e32394. doi: 10.1016/j.heliyon.2024.e32394. eCollection 2024 Jun 15.

Abstract

OBJECTIVE

Percutaneous nephrolithotomy (PCNL) is the main method for pyonephrosis or lithotripsy in urology. However, it often comes with high risk, as the inaccurate puncture inevitably causes bleeding, intra- and post-operative complications. So, a new inter-disciplinary approach is needed to perform the puncture more accurately.

METHODS

3 signs made of lead were marked onto the skin of the posterior side of the waist of a domestic pig or a patient, which was scanned by computed tomography (CT). Based on the CT images, the computer design and the 3D printing, a navigation template made of the transparent resin material is constructed. They were attached onto the surgical area on pig or patient according to the signs. During the PCNL, with this template, the puncture position, angle and depth were optimized in order to precisely enter the targeted renal pelvis or calices.

RESULTS

With the 3D navigation templates, 18G puncture needles were used to enter the renal pelvis upon performing the PCNL on a porcine model and a patient. On the porcine model, the urine outflow was observed with minimal complication. Post-operative CT scans revealed that the needle was located in the renal pelvis. For the patient case, the puncture point was designed to target the calix with stone. No obvious bleeding and complication was found in renal puncture with template.

CONCLUSIONS

The navigation template was made with the combination of 3D printing, CT images and computer design. This template allows for accurate puncture of the renal pelvis or calix. Surgical improvement in kidney stones and pyonephrosis was observed in porcine model and patient case. In the future, prospective, trandomized, controlled clinical trials are needed to further confirm its advantage.

摘要

目的

经皮肾镜取石术(PCNL)是泌尿外科治疗肾积脓或碎石的主要方法。然而,该手术风险通常较高,因为穿刺不准确不可避免地会导致出血、术中及术后并发症。因此,需要一种新的跨学科方法来更精确地进行穿刺。

方法

在一头家猪或患者的腰部后侧皮肤上标记3个铅制标记物,然后进行计算机断层扫描(CT)。基于CT图像、计算机设计和3D打印,构建一个由透明树脂材料制成的导航模板。根据标记物将其附着在猪或患者的手术区域。在PCNL手术过程中,利用该模板优化穿刺位置、角度和深度,以便精确进入目标肾盂或肾盏。

结果

使用3D导航模板,在猪模型和患者身上进行PCNL时,用18G穿刺针进入肾盂。在猪模型上,观察到尿液流出,并发症极少。术后CT扫描显示穿刺针位于肾盂内。对于患者病例,穿刺点设计为针对有结石的肾盏。使用模板进行肾穿刺时未发现明显出血和并发症。

结论

导航模板是通过3D打印、CT图像和计算机设计相结合制成的。该模板可实现肾盂或肾盏的精确穿刺。在猪模型和患者病例中均观察到肾结石和肾积脓手术有改进。未来,需要进行前瞻性、随机、对照临床试验以进一步证实其优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0fa/11214351/e1825dc9bb03/gr1.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验