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妊娠期嗜铬细胞瘤:高血压的一个隐匿病因

Pheochromocytoma During Pregnancy: A Hidden Cause for Hypertension.

作者信息

Monteiro Sidonie, Rodrigues Raquel, Almeida Amélia, Monteiro Maria José

机构信息

Obstetrics and Gynecology, Unidade Local de Saúde (ULS) do Médio Ave, Vila Nova de Famalicão, PRT.

Obstetrics and Gynecology, Unidade Local de Saúde (ULS) de Braga, Braga, PRT.

出版信息

Cureus. 2024 May 29;16(5):e61286. doi: 10.7759/cureus.61286. eCollection 2024 May.

Abstract

Pheochromocytoma, a rare but potentially serious condition, poses challenges in timely identification, especially during pregnancy due to misconceptions about pregnancy-related hypertension causes. However, paroxysmal symptoms heighten diagnostic suspicion. The diagnosis relies on biochemical confirmation of catecholamine hypersecretion followed by imaging for tumor localization. When diagnosed at or after 24 weeks, alpha-adrenoceptor blockers are recommended during pregnancy to manage catecholamine excess, delaying tumor removal until viability or post-delivery. The rarity of this condition during pregnancy, coupled with diagnostic and management challenges, underscores its importance for obstetric professionals in addressing hypertensive control, delivery timing, and surgical intervention.

摘要

嗜铬细胞瘤是一种罕见但可能严重的病症,在及时识别方面存在挑战,尤其是在孕期,因为人们对妊娠相关高血压的病因存在误解。然而,阵发性症状会增加诊断怀疑。诊断依赖于儿茶酚胺分泌过多的生化确认,随后进行肿瘤定位成像。在孕24周及以后诊断出时,建议在孕期使用α-肾上腺素能受体阻滞剂来控制儿茶酚胺过量,将肿瘤切除推迟至胎儿存活或产后。这种病症在孕期的罕见性,加上诊断和管理方面的挑战,凸显了其对于产科专业人员在控制高血压、确定分娩时机和手术干预方面的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/004b/11211965/fec03b21985e/cureus-0016-00000061286-i01.jpg

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