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2014年至2023年氯胺酮的研究趋势与热点:一项文献计量分析

Research trends and hotspots of ketamine from 2014 to 2023: a bibliometric analysis.

作者信息

Wang Yida, Chang Sile, Chen Dongxu

机构信息

Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Science, Sichuan University, Chengdu, China.

Department of Anesthesiology, West China Second Hospital, Sichuan University, Chengdu, China.

出版信息

Front Neurosci. 2024 Jun 14;18:1407301. doi: 10.3389/fnins.2024.1407301. eCollection 2024.

DOI:10.3389/fnins.2024.1407301
PMID:38948929
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11211255/
Abstract

BACKGROUND

Despite this growing interest, there remains a lack of comprehensive and systematic bibliometric analyses of ketamine research. This study aimed to summarize the progress in ketamine research through bibliometric analysis, providing insights into the development and direction of the field.

METHODS

Publications related to ketamine were retrieved from the Web of Science Core Collection (WoSCC) database on February 15, 2024. In conducting a comprehensive bibliometric analysis, a variety of bibliographic elements were meticulously collected to map the landscape of research within a specific field.

RESULTS

Between January 1, 2014, and December 31, 2023, a total of 10,328 articles on ketamine research were published across 1,752 academic journals by 45,891 authors from 8,914 institutions in 128 countries. The publication volume has shown a steady increase over this period. The United States of America (USA) and the People's Republic of China lead in both publication and citation counts. The National Institute of Mental Health (NIMH) and Yale University emerge as the most active institutions in this research domain. Carlos Zarate of the NIH National Institute of Mental Health was noted for the highest number of significant publications and received the most co-citations. The analysis revealed key research themes including mechanism of action, adverse events, psychiatric applications, and perioperative implications.

CONCLUSION

This study provided comprehensive bibliometric and knowledge mapping analysis of the global ketamine research landscape, offering valuable insights into the trends, key contributors, and thematic focus areas within the field. By delineating the evolution of ketamine research, this study aims to guide future scholarly endeavors and enhance our understanding of ketamine's therapeutic potential.

摘要

背景

尽管对此兴趣日益浓厚,但氯胺酮研究仍缺乏全面系统的文献计量分析。本研究旨在通过文献计量分析总结氯胺酮研究的进展,为该领域的发展和方向提供见解。

方法

2024年2月15日从科学引文索引核心合集(WoSCC)数据库中检索与氯胺酮相关的出版物。在进行全面的文献计量分析时,精心收集了各种文献元素,以描绘特定领域内的研究概况。

结果

在2014年1月1日至2023年12月31日期间,来自128个国家8914个机构的45891名作者在1752种学术期刊上发表了共计10328篇关于氯胺酮研究的文章。在此期间,出版物数量呈稳步增长。美国和中华人民共和国在出版物数量和被引次数方面均领先。美国国立精神卫生研究所(NIMH)和耶鲁大学是该研究领域最活跃的机构。美国国立精神卫生研究所的卡洛斯·萨拉特发表的重要出版物数量最多,获得的共被引次数也最多。分析揭示了关键研究主题,包括作用机制、不良事件、精神科应用和围手术期影响。

结论

本研究对全球氯胺酮研究格局进行了全面的文献计量和知识图谱分析,为该领域的趋势、主要贡献者和主题重点领域提供了有价值的见解。通过描绘氯胺酮研究的演变,本研究旨在指导未来的学术努力,并增进我们对氯胺酮治疗潜力的理解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41eb/11211255/d9260ca0983e/fnins-18-1407301-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41eb/11211255/81e85a5abc92/fnins-18-1407301-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41eb/11211255/2cc57163afea/fnins-18-1407301-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41eb/11211255/405aa7ea23c6/fnins-18-1407301-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41eb/11211255/9447377acdfa/fnins-18-1407301-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41eb/11211255/682fa651daa3/fnins-18-1407301-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41eb/11211255/d9260ca0983e/fnins-18-1407301-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41eb/11211255/81e85a5abc92/fnins-18-1407301-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41eb/11211255/fcd5ae9605ca/fnins-18-1407301-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41eb/11211255/2cc57163afea/fnins-18-1407301-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41eb/11211255/405aa7ea23c6/fnins-18-1407301-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41eb/11211255/9447377acdfa/fnins-18-1407301-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41eb/11211255/682fa651daa3/fnins-18-1407301-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41eb/11211255/d9260ca0983e/fnins-18-1407301-g007.jpg

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本文引用的文献

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So how special is special K? A systematic review and meta-analysis of ketamine for PTSD RCTs.那么,K 粉有何特别之处呢?一项对 PTSD RCT 中氯胺酮的系统评价和荟萃分析。
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Ketamine's rapid antidepressant effects are mediated by Ca-permeable AMPA receptors.氯胺酮的快速抗抑郁作用是由 Ca 通透性 AMPA 受体介导的。
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NMDA Receptor Activation-Dependent Antidepressant-Relevant Behavioral and Synaptic Actions of Ketamine.氯胺酮激活 NMDA 受体的抗抑郁作用及相关的行为和突触效应。
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