Lee Heonwoo, An Hyeong Rok, Kim Chan Wook, Park Young Soo
Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Division of Colon and Rectal Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
J Pathol Transl Med. 2024 Jul;58(4):198-200. doi: 10.4132/jptm.2024.06.04. Epub 2024 Jul 3.
Colonic duplication constitutes a rare congenital anomaly, characterized by the presence of hollow cystic or tubular structures exhibiting an epithelial-lined intestinal wall. Diagnostic challenges persist due to its low incidence and manifestation of nonspecific symptoms such as abdominal pain or constipation, resulting in a reluctance to pursue surgical resection. As associated malignancies in colonic duplication are rare, the inherent malignant potential of these anomalies remains undetermined. Additionally, despite reported instances of associated malignancies in colonic duplication, there is an absence of reports in the literature detailing tubular adenoma within these cases. The histologic features of the presented case are particularly noteworthy, situated at the precancerous stage, intimating potential progression towards adenocarcinoma within colonic duplication.
结肠重复畸形是一种罕见的先天性异常,其特征是存在具有内衬上皮的肠壁的中空囊性或管状结构。由于其发病率低且表现为腹痛或便秘等非特异性症状,诊断面临挑战,导致不愿进行手术切除。由于结肠重复畸形相关的恶性肿瘤很少见,这些异常的内在恶性潜能仍未确定。此外,尽管有报道称结肠重复畸形存在相关恶性肿瘤,但文献中没有详细描述这些病例中管状腺瘤的报道。本病例的组织学特征特别值得注意,处于癌前阶段,提示结肠重复畸形内有向腺癌进展的潜在可能。