Harayama Eisei, Goto Kei, Yamauchi Kota
Department of Rehabilitation, Steel Memorial Yawata Hospital: 1-1-1 Harunomachi, Yawatahigasi-ku, Kitakyushu-shi, Fukuoka 805-0050, Japan.
J Phys Ther Sci. 2024 Jul;36(7):396-401. doi: 10.1589/jpts.36.396. Epub 2024 Jul 1.
[Purpose] Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disease characterized by decreased transmitter secretion from neuromuscular junctions and nerve terminals. Such cases require physical therapy for independently performing daily activities; however, care must be taken to avoid overwork weakness. This study aimed to investigate the effects of aerobic exercise-based physical therapy in patients with LEMS. [Participants and Methods] We report a case of LEMS with decreased muscle endurance due to inactivity. The participant was subjected to physical therapy with an exercise modality-improved muscle endurance with low-intensity repetitions, while monitoring subjective exercise intensity over time. [Results] The participant achieved independence activities of daily living without developing overwork weakness. [Conclusion] Appropriate physical therapy is an important aspect in treating LEMS.
[目的] 兰伯特-伊顿肌无力综合征(LEMS)是一种自身免疫性疾病,其特征为神经肌肉接头和神经末梢的递质分泌减少。此类病例需要进行物理治疗以独立完成日常活动;然而,必须注意避免过劳性肌无力。本研究旨在调查基于有氧运动的物理治疗对LEMS患者的影响。[参与者与方法] 我们报告一例因缺乏活动导致肌肉耐力下降的LEMS病例。该参与者接受了物理治疗,采用了一种运动方式——通过低强度重复运动提高肌肉耐力,同时随时间监测主观运动强度。[结果] 该参与者实现了日常生活活动的独立,且未出现过劳性肌无力。[结论] 适当的物理治疗是治疗LEMS的一个重要方面。