California Pacific Medical Center, Department of Ophthalmology, San Francisco, California.
Mayo Clinic Department of Radiology, Rochester, Minnesota.
J AAPOS. 2024 Aug;28(4):103964. doi: 10.1016/j.jaapos.2024.103964. Epub 2024 Jun 30.
We investigated the relationship between optic nerve (ON) size and visual acuity in children with optic nerve hypoplasia (ONH). The medical records of patients <19 years with ONH who underwent brain magnetic resonance imaging (MRI) and visual acuity assessment were reviewed. ON diameter at orbital and cisternal segments was assessed independently by two neuroradiologists and compared with visual acuity. ON diameter <1.7 mm represented a cutoff, below which was significantly associated with visual acuity of 20/200 or worse (P = 0.04) and above which was significantly associated with visual acuity of 20/40 or better (P = 0.004). ON diameter measured with MRI may provide an early prognostic indication of visual potential for children with ONH.
我们研究了视神经（ON）大小与视神经发育不良（ONH）儿童视力之间的关系。对接受脑磁共振成像（MRI）和视力评估的 <19 岁视神经发育不良患者的病历进行了回顾。两名神经放射科医生分别评估了眼眶段和鞍上池段的视神经直径，并与视力进行了比较。视神经直径<1.7 毫米为截断值，低于该值与视力为 20/200 或更差显著相关（P=0.04），高于该值与视力为 20/40 或更好显著相关（P=0.004）。MRI 测量的视神经直径可能为视神经发育不良儿童的视觉潜力提供早期预后指标。
