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肩关节僵硬的危险因素和预测模型。

Risk factors and predictive models for frozen shoulder.

机构信息

Department of Joint Surgery, Suining Central Hospital, Suining City, 629000, Sichuan Province, China.

Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan Province, China.

出版信息

Sci Rep. 2024 Jul 3;14(1):15261. doi: 10.1038/s41598-024-66360-y.

Abstract

This study aims to explore the risk factors associated with frozen shoulder (FS) and develop a predictive model for diagnosing FS, in order to facilitate early detection of the condition. A total of 103 patients diagnosed with FS and admitted to the Department of Joint Surgery at Suining Central Hospital between October 2021 and October 2023 were consecutively included in the study. Additionally, 309 individuals without shoulder joint diseases, matched for age and gender, who visited the department during the same time, were included as the control group.The complete recording of clinical data for all patients was followed by the utilization of statistical tests such as the Mann-Whitney U test, sample t test, and chi-square test to compare different groups. Additionally, multivariate binary logistic regression analysis was employed to identify risk factors associated with the occurrence of FS in patients, leading to the establishment of a prediction model and derivation of a simplified equation. The diagnostic effectiveness of individual indicators and prediction models was assessed through the use of receiver operating characteristic (ROC) curve analysis. In the sample of 103 individuals, 35 were identified as male and 68 as female, with an average age range of 40-70 years (mean age: 54.20 ± 6.82 years). The analysis conducted between different groups revealed that individuals with a low body mass index (BMI), in conjunction with other factors such as diabetes, cervical spondylosis, atherosclerosis, and hyperlipidemia, were more susceptible to developing FS. Logistic regression analysis further indicated that low BMI, diabetes, cervical spondylosis, and hyperlipidemia were significant risk factors for the occurrence of FS. These variables were subsequently incorporated into a predictive model, resulting in the creation of a simplified equation.The ROC curve demonstrated that the combined indicators in the predictive model exhibited superior diagnostic efficacy compared to single indicators, as evidenced by an area under the curve of 0.787, sensitivity of 62.1%, and specificity of 82.2%. Low BMI, diabetes, cervical spondylosis, and hyperlipidemia are significant risk factors associated with the occurrence of FS. Moreover, the utilization of a prediction model has demonstrated superior capability in forecasting the likelihood of FS compared to relying solely on individual indicators. This finding holds potential in offering valuable insights for the early diagnosis of FS.

摘要

本研究旨在探讨与冻结肩(FS)相关的危险因素,并建立诊断 FS 的预测模型,以促进对该病的早期发现。我们连续纳入了 2021 年 10 月至 2023 年 10 月期间在遂宁市中心医院关节外科就诊的 103 例 FS 患者作为病例组,同时纳入了 309 例年龄和性别相匹配的无肩关节疾病的个体作为对照组。我们对所有患者的临床资料进行了详细记录,并采用 Mann-Whitney U 检验、样本 t 检验和卡方检验等统计学方法对不同组间进行比较。此外,我们还采用多因素二元逻辑回归分析来识别与 FS 发生相关的危险因素,从而建立预测模型并推导出简化方程。我们通过受试者工作特征(ROC)曲线分析评估了各个指标和预测模型的诊断效能。在这 103 例患者中,男性 35 例,女性 68 例,年龄范围为 40-70 岁,平均年龄为 54.20±6.82 岁。不同组间的分析表明,BMI 低、合并糖尿病、颈椎病、动脉粥样硬化和高脂血症的个体更容易发生 FS。逻辑回归分析进一步表明,BMI 低、糖尿病、颈椎病和高脂血症是 FS 发生的显著危险因素。这些变量随后被纳入预测模型,从而建立了简化方程。ROC 曲线显示,预测模型中的联合指标的诊断效能优于单一指标,曲线下面积为 0.787,灵敏度为 62.1%,特异度为 82.2%。BMI 低、糖尿病、颈椎病和高脂血症是 FS 发生的显著危险因素。此外,与仅依赖于单一指标相比,使用预测模型在预测 FS 的可能性方面具有更好的能力。这一发现为 FS 的早期诊断提供了有价值的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecf3/11220144/dc400b12ddc5/41598_2024_66360_Fig1_HTML.jpg

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