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是否存在亚极型结核样病例?

[Are there subpolar tuberculoid cases?].

作者信息

Saul A, Novales J

出版信息

Acta Leprol. 1985 Jan-Mar;3(1):29-35.

PMID:3895802
Abstract

The idea of the existence of subpolar tuberculoid cases is supported on the spectral conception of Ridley and Jopling who included the subpolar lepromatous patients between LL and BL cases. According with Languillon, we have studied 40 tuberculoid cases to find out clinical, bacteriological, immunological and histopathological parameters of subpolar T cases. The subpolar T cases do exist, they are unstable cases which can slide through the immunological spectrum towards the L pole. These cases are characterized by numerous, symmetrical, dysesthetic tuberculoid lesions with an important neural involvement. Bacilli can be found in a small number in the smears of nasal mucosae in some cases. Mitsuda reaction is always positive and histopathologically the granulomas, lymphocytes and epithelioid cells are in less number without the epidermotropism which is very often seen in polar T cases.

摘要

亚极量结核样型病例存在的观点得到了里德利和乔普林光谱概念的支持,他们将亚极量瘤型患者纳入了瘤型(LL)和界线类偏瘤型(BL)病例之间。根据朗吉永的研究,我们对40例结核样型病例进行了研究,以找出亚极量结核样型(T)病例的临床、细菌学、免疫学和组织病理学参数。亚极量结核样型病例确实存在,它们是不稳定的病例,可通过免疫光谱向瘤型极移动。这些病例的特征是有许多对称的、感觉异常的结核样病变,并伴有重要的神经受累。在某些病例中,鼻黏膜涂片可发现少量杆菌。密特反应始终为阳性,组织病理学上肉芽肿、淋巴细胞和上皮样细胞数量较少,且无极地结核样型病例中常见的亲表皮现象。

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