Pinilla L, Aguilar R, Bellido C, Aguilar E
Andrologia. 1985 May-Jun;17(3):254-6. doi: 10.1111/j.1439-0272.1985.tb00998.x.
The LH response to 100 or 1000 ng of LH-RH was studied in adult male rats treated neonatally with 500 micrograms of estradiol benzoate or olive oil. The dose of 100 ng elicited the same LH increase in both groups, but the estrogenized animals responded more when 1000 ng of LH-RH was injected. These data suggest that the decreased LH response to orchidectomy found in estrogenized animals is not due to a failure in pituitary responsiveness to LH-RH.
研究了新生期用500微克苯甲酸雌二醇或橄榄油处理的成年雄性大鼠对100或1000纳克促黄体生成素释放激素（LH-RH）的促黄体生成素（LH）反应。100纳克的剂量在两组中引起相同的LH升高，但当注射1000纳克LH-RH时，经雌激素处理的动物反应更强。这些数据表明，在经雌激素处理的动物中发现的对睾丸切除术后LH反应降低并非由于垂体对LH-RH反应性的失败。
