Catalano M, Libretti A
Angiology. 1985 May;36(5):293-6. doi: 10.1177/000331978503600505.
Many epidemiological studies have shown up the frequent association of arterial hypertension (HT) with atherosclerosis of different localizations. However, many of the drugs used to treat HT are contraindicated in patients with peripheral vascular disease (PVD), because they cause unfavorable metabolic changes or vasoconstriction. The aim of the present study was to assess the effect of a proven hypotensive drug, captopril, on the peripheral circulation. The drug appeared to be effective in improving blood flow to lower limbs, prolonging the pain. Free interval and increasing the angle/arm arterial pressure index.
许多流行病学研究表明，动脉高血压（HT）与不同部位的动脉粥样硬化经常相关。然而，许多用于治疗HT的药物在患有外周血管疾病（PVD）的患者中是禁忌的，因为它们会引起不良的代谢变化或血管收缩。本研究的目的是评估一种经证实的降压药物卡托普利对外周循环的影响。该药物似乎在改善下肢血流、延长疼痛-free间隔以及增加踝/臂动脉压指数方面有效。 （注：原文中“prolonging the pain. Free interval”表述似乎有误，推测可能是“prolonging the pain-free interval”，翻译中按推测后的正确表述翻译）
