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腹膜后盆腔神经鞘瘤的影像学特征及临床分析:病例报告。

Image features and clinical analysis of retroperitoneal pelvic schwannoma: a case report.

机构信息

Department of Ultrasonography, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shuaifuyuan NO.1, Dongcheng District, Beijing, China.

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shuaifuyuan NO.1, Dongcheng District, Beijing, China.

出版信息

BMC Neurol. 2024 Jul 3;24(1):230. doi: 10.1186/s12883-024-03715-y.

Abstract

BACKGROUND

Schwannomas are benign usually encapsulated nerve sheath tumors derived from the Schwann cells, and affecting single or multiple nerves. The tumors commonly arise from the cranial nerves as acoustic neurinomas but they are extremely rare in the pelvis and the retroperitoneal area. Retroperitoneal pelvic schwannomas often present with non-specific symptoms leading to misdiagnosis and prolonged morbidity.

CASE PRESENTATION

We report the case of a 59-year-old woman presenting with a feeling of heaviness in the lower abdomen who was found to have a retroperitoneal pelvic schwannoma originating from the right femoral nerve. She had a history of two resections of peripheral schwannomas at four different sites of limbs. After conducting magnetic resonance imaging, this pelvic schwannoma was misdiagnosed as a gynecological malignancy. The tumor was successfully removed by laparoscopic surgery. Pathological analysis of the mass revealed a benign schwannoma of the femoral nerve sheath with demonstrating strong, diffuse positivity for S-100 protein.

CONCLUSIONS

Although retroperitoneal pelvic schwannoma is rare, it should be considered in the differential diagnosis of pelvic masses, especially in patients with a history of neurogenic mass or the presence of neurogenic mass elsewhere.

摘要

背景

神经鞘瘤是良性的、通常有包膜的神经鞘肿瘤,来源于施万细胞,可影响单一或多条神经。这些肿瘤通常起源于颅神经,如听神经瘤,但在骨盆和腹膜后区域极为罕见。腹膜后盆腔神经鞘瘤常表现为非特异性症状,导致误诊和延长病程。

病例介绍

我们报告了一例 59 岁女性,下腹有沉重感,发现源自右侧股神经的腹膜后盆腔神经鞘瘤。她曾有四肢四个不同部位的外周神经鞘瘤切除术史。进行磁共振成像后,该盆腔神经鞘瘤被误诊为妇科恶性肿瘤。该肿瘤通过腹腔镜手术成功切除。肿块的病理分析显示为股神经鞘的良性神经鞘瘤,S-100 蛋白呈强弥漫阳性。

结论

尽管腹膜后盆腔神经鞘瘤罕见,但在盆腔肿块的鉴别诊断中应考虑到它,尤其是在有神经源性肿块病史或其他部位存在神经源性肿块的患者中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58c0/11221090/1316b0e6204e/12883_2024_3715_Fig1_HTML.jpg

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