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面神经多发性神经鞘瘤误诊为颈淋巴瘤:一例报告。

Multiple schwannomas of the facial nerve mimicking cervical lymphoma: a case report.

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Saarland University Medical Center, Kirrbergerstr. 100, building 6, 66421, Homburg, Germany.

Department of General and Surgical Pathology, Saarland University Medical Center, 66421, Homburg, Germany.

出版信息

J Med Case Rep. 2021 Aug 20;15(1):436. doi: 10.1186/s13256-021-03006-x.

Abstract

BACKGROUND

In this report, we describe the first case in literature of a patient with multiple schwannomas of the marginal mandibular branch of the facial nerve.

CASE PRESENTATION

A Caucasian patient presented with a sudden onset of left lower facial nerve palsy House-Brackmann score III for 1 month. Computed tomography imaging was performed to exclude a cerebral event and revealed multiple tumors within the left parotid gland. Duplex ultrasound and magnetic resonance imaging scans delineated multiple, hypoechoic tumors, round in shape and well defined without a hilar structure along the left mandible. For histological verification, a left-side partial parotidectomy and extirpation of an intraparotideal node was performed with use of a nerve-integrity monitor. Histomorphological analysis of the resected tissue revealed a benign schwannoma. Facial nerve function remained unchanged since the operation. The size of the nonresected tumors is currently monitored regularly by ultrasonography. Fibromatosis has been excluded.

CONCLUSIONS

If multiple tumors occur in the parotid gland and the angle of the jaw, schwannomas need to be considered as a differential diagnosis. To plan the right diagnostic surgical intervention and prevent nerve damage, a thorough ultrasound examination is essential in preoperative diagnostic work-up for any suspicious lesion of the parotid gland and jaw region.

摘要

背景

在本报告中,我们描述了首例面神经下颌缘支多发性神经鞘瘤患者。

病例介绍

一名高加索患者突发左侧面神经下部瘫痪,House-Brackmann 评分为 III 级,持续 1 个月。为排除脑部疾病进行了计算机断层扫描成像,结果显示左侧腮腺内有多个肿瘤。双功能超声和磁共振成像扫描显示,左侧下颌骨沿线上存在多个圆形、边界清晰的低回声肿瘤,但无门脉结构。为了进行组织学验证,使用神经完整性监测仪进行了左侧部分腮腺切除术和腮腺内淋巴结切除术。切除组织的组织形态学分析显示为良性神经鞘瘤。自手术后,面神经功能无变化。目前,通过超声检查定期监测未切除肿瘤的大小。已排除纤维瘤病。

结论

如果腮腺和下颌角出现多个肿瘤,需要考虑神经鞘瘤作为鉴别诊断。为了计划正确的诊断性手术干预并防止神经损伤,在术前对腮腺和下颌区域任何可疑病变进行诊断性检查时,彻底的超声检查至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c9b/8377860/cfeb203aea2b/13256_2021_3006_Fig1_HTML.jpg

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