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神经旁锁骨上肌阻滞在关节镜肩手术中对膈神经的保护作用:一项随机对照试验。

Diaphragm-sparing efficacy of subparaneural upper trunk block for arthroscopic shoulder surgery: A randomised controlled trial.

机构信息

From the Department of Anaesthesiology and Pain Medicine (YJ, CO, DL, SS, WC, CL, SYL, BH) and Department of Orthopaedic Surgery, Chungnam National University Hospital, College of Medicine, Chungnam National University, Daejeon, South Korea (W-YL).

出版信息

Eur J Anaesthesiol. 2024 Oct 1;41(10):760-768. doi: 10.1097/EJA.0000000000002034. Epub 2024 Jul 3.

Abstract

BACKGROUND

Inter-scalene block (ISB) is associated with an inevitable risk of hemi-diaphragmatic paresis (HDP). To reduce the risk of HDP, an upper trunk block (UTB) has been proposed at the brachial plexus division level.

OBJECTIVE

We hypothesised that UTB would be associated with a lower incidence of HDP than ISB while providing sufficient analgesia following arthroscopic shoulder surgery.

DESIGN

Randomised controlled trial.

SETTING

A tertiary teaching hospital.

PATIENTS

Seventy patients aged 20 to 80 years undergoing arthroscopic rotator cuff repair.

INTERVENTION

Ultrasound-guided ISB or UTB was performed with 5 ml 0.75% ropivacaine.

MAIN OUTCOME MEASURES

The primary outcome was the incidence of complete HDP, assessed by diaphragm excursion using ultrasound, defined as a decrease to 25% or less of baseline or occurrence of paradoxical movement. Postoperative pulmonary function change, pain scores, opioid consumption and pain-related outcomes were the secondary outcomes.

RESULTS

The UTB group had a significantly lower incidence of complete HDP than the ISB group [5.9% (2/34) vs. 41.7% (15/36); absolute difference, 35.8%; 95% confidence interval (CI), 17.8 to 53.7%; P  < 0.001]. The postblockade decline in pulmonary function was more pronounced in the ISB group than that in the UTB group. The pain score at 1 h postoperatively was not significantly different between the groups (ISB vs. UTB group: median 0 vs. 1; median difference, -1; 95% CI, -2 to 0.5). No significant difference was observed in any other secondary outcomes.

CONCLUSION

UTB was associated with a lower incidence of HDP compared with ISB while providing excellent analgesia in arthroscopic shoulder surgery.

TRIAL REGISTRATION

Clinical Trial Registry of Korea ( https://cris.nih.go.kr ) identifier: KCT0007002.

IRB NUMBER

Chungnam National University Hospital Institutional Review Board No. 2021-12-069.

摘要

背景

经斜角肌间隙阻滞(ISB)会导致膈肌部分麻痹(HDP),为降低 HDP 风险,有人提出在臂丛神经干水平行高位肌间沟阻滞(UTB)。

目的

我们假设与 ISB 相比,UTB 用于行关节镜下肩袖修复术时,发生 HDP 的风险更低,且能提供足够的镇痛效果。

设计

随机对照试验。

设置

三级教学医院。

患者

70 例年龄 20~80 岁、行关节镜下肩袖修复术的患者。

干预

超声引导下行 ISB 或 UTB,均使用 0.75%罗哌卡因 5ml。

主要结局指标

主要结局为通过超声测量膈肌移动度评估完全性 HDP 的发生率,定义为较基线降低 25%或更多或出现反常运动。次要结局为术后肺功能改变、疼痛评分、阿片类药物用量和与疼痛相关的结局。

结果

与 ISB 组相比,UTB 组完全性 HDP 的发生率显著更低[5.9%(2/34)比 41.7%(15/36);绝对差值为 35.8%;95%置信区间(CI)为 17.8%~53.7%;P <0.001]。ISB 组较 UTB 组术后肺功能下降更明显。术后 1 h 疼痛评分在两组间无显著差异(ISB 组 vs. UTB 组:中位数 0 分比 1 分;中位数差值-1 分;95%CI-2 分至 0.5 分)。其他次要结局也无显著差异。

结论

与 ISB 相比,UTB 用于行关节镜下肩袖修复术时可降低 HDP 的发生率,且能提供良好的镇痛效果。

试验注册

韩国临床试验注册中心( https://cris.nih.go.kr ),标识符:KCT0007002。

机构审查委员会

忠南国立大学医院机构审查委员会,编号:2021-12-069。

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