金属有机框架及其复合材料连续流合成的最新进展。

Recent advances in continuous flow synthesis of metal-organic frameworks and their composites.

作者信息

Senthil Raja Duraisamy, Tsai De-Hao

机构信息

Department of Chemical Engineering, National Tsing Hua University, No. 101, Sec. 2, Kuang-Fu Rd., 300044 Hsinchu City, Taiwan, Republic of China.

出版信息

Chem Commun (Camb). 2024 Aug 9;60(65):8497-8515. doi: 10.1039/d4cc02088j.

Abstract

Metal-organic frameworks (MOFs) and their composites have garnered significant attention in recent years due to their exceptional properties and diverse applications across various fields. The conventional batch synthesis methods for MOFs and their composites often suffer from challenges such as long reaction times, poor reproducibility, and limited scalability. Continuous flow synthesis has emerged as a promising alternative for overcoming these limitations. In this short review, we discuss the recent advancements, challenges, and future perspectives of continuous flow synthesis in the context of MOFs and their composites. The review delves into a brief overview of the fundamental principles of flow synthesis, highlighting its advantages over batch methods. Key benefits, including precise control over reaction parameters, improved scalability and efficiency, rapid optimization capabilities, enhanced reaction kinetics and mass transfer, and increased safety and environmental sustainability, are addressed. Additionally, the versatility and flexibility of flow synthesis techniques are discussed. The article then explores various flow synthesis methods applicable to MOF and MOF composite production. The techniques covered include continuous flow solvothermal synthesis, mechanochemical synthesis, microwave and ultrasound-assisted flow synthesis, microfluidic droplet synthesis, and aerosol synthesis. Notably, the combination of flow chemistry and aerosol synthesis with real-time characterization is also addressed. Furthermore, the impact of flow synthesis on the properties and performance of MOFs is explored. Finally, the review discusses current challenges and future perspectives in the field of continuous flow MOF synthesis, paving the way for further development and broader application of this promising technique.

摘要

金属有机框架材料(MOFs)及其复合材料近年来因其优异的性能和在各个领域的广泛应用而备受关注。传统的MOFs及其复合材料的间歇合成方法常常面临诸如反应时间长、重现性差和可扩展性有限等挑战。连续流动合成作为克服这些局限性的一种有前途的替代方法应运而生。在这篇简短的综述中,我们讨论了在MOFs及其复合材料背景下连续流动合成的最新进展、挑战和未来展望。该综述深入简要概述了流动合成的基本原理,突出了其相对于间歇方法的优势。阐述了关键益处,包括对反应参数的精确控制、提高的可扩展性和效率、快速优化能力、增强的反应动力学和传质以及提高的安全性和环境可持续性。此外,还讨论了流动合成技术的多功能性和灵活性。文章接着探讨了适用于MOF和MOF复合材料生产的各种流动合成方法。涵盖的技术包括连续流动溶剂热合成、机械化学合成、微波和超声辅助流动合成、微流控液滴合成和气溶胶合成。值得注意的是,还讨论了流动化学和气溶胶合成与实时表征的结合。此外,还探讨了流动合成对MOFs性质和性能的影响。最后,该综述讨论了连续流动MOF合成领域当前的挑战和未来展望,为这一有前途的技术的进一步发展和更广泛应用铺平了道路。

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