Department of Epidemiology, Capital Institute of Pediatrics, Beijing, China.
Tianjin Women's and Children's Health Center, Tianjin, China.
Nutrition. 2024 Sep;125:112500. doi: 10.1016/j.nut.2024.112500. Epub 2024 May 27.
The purpose of the present study was to explore the latent growth trajectory of body mass index (BMI) from birth to 24 months and comprehensively analyze body composition development influencing factor in preschool children.
This ambidirectional cohort study was conducted in Tianjin, China, from 2017 to 2020, and children's regular medical check-up data from birth to 24 months were retrospectively collected. The growth models were used to fit BMI z-score trajectories for children aged 0-24 months. Crossover analysis and interaction model were used to explore the interaction of influencing factors.
We analyzed the growth trajectories of 3217 children, of these, 1493 children with complete follow-up data were included in the influencing factors analysis. Trajectories and parental prepregnancy BMI (ppBMI) were independent factors influencing children's body composition. When paternal ppBMI ≥24 kg/m, regardless of maternal ppBMI, the risk of overweight and obesity in senior-class children was increased. The high trajectories played a partial mediating role in the association between paternal ppBMI and body composition in preschool children.
BMI growth in children aged 0-24 months can be divided into three latent trajectories: low, middle, and high. These trajectories and parental ppBMI were independent and interactive factors influencing children's body composition. The high trajectories played a partial mediating role in the association between paternal ppBMI and body composition in preschool children. It is necessary to pay attention to the BMI growth level of children aged 0-24 months, which plays an important role in the development of body fat in the future.
本研究旨在探讨儿童从出生到 24 个月时体重指数（BMI）的潜在增长轨迹，并综合分析学龄前儿童体成分发育的影响因素。
本双向队列研究于 2017 年至 2020 年在中国天津进行，回顾性收集了儿童从出生到 24 个月的定期体检数据。使用生长模型拟合 0-24 个月儿童 BMI z 评分轨迹。采用交叉分析和交互模型探讨影响因素的交互作用。
我们分析了 3217 名儿童的生长轨迹，其中 1493 名具有完整随访数据的儿童纳入了影响因素分析。轨迹和父母孕前 BMI（ppBMI）是影响儿童体成分的独立因素。当父亲的 ppBMI≥24 kg/m²时，无论母亲的 ppBMI 如何，高年级儿童超重和肥胖的风险都会增加。高轨迹在父亲的 ppBMI 与学龄前儿童体成分之间的关联中起部分中介作用。
0-24 个月儿童 BMI 的增长可分为三个潜在轨迹：低、中、高。这些轨迹和父母的 ppBMI 是影响儿童体成分的独立和交互因素。高轨迹在父亲的 ppBMI 与学龄前儿童体成分之间的关联中起部分中介作用。有必要关注 0-24 个月儿童的 BMI 增长水平，这对未来体脂肪的发育起着重要作用。
