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临床处理大咯血:围手术期关注病因与处理

Clinical Approach to Massive Hemoptysis: Perioperative Focus on Causes and Management.

机构信息

Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore.

Department of Anaesthesiology, Singapore General Hospital, Singapore; Department of Cardiothoracic Anaesthesia, National Heart Centre, Singapore.

出版信息

J Cardiothorac Vasc Anesth. 2024 Oct;38(10):2412-2425. doi: 10.1053/j.jvca.2024.06.002. Epub 2024 Jun 5.

Abstract

Massive hemoptysis is a time critical airway emergency in the perioperative setting, with an associated mortality exceeding 50%. Causes of hemoptysis in the perioperative setting include procedural complication, coagulopathy, malignancy, chronic lung disease, infection, left-sided cardiac disease, pulmonary vascular disease and autoimmune disease. A rapid and coordinated multidisciplinary response is required to secure the airway, isolate the lung, ensure adequate oxygenation and ventilation, identify the underlying cause and initiate specific systemic, bronchoscopic, endovascular, or surgical treatment. This review examines the etiology, pathophysiology, as well as approach to management and interventions in perioperative massive hemoptysis.

摘要

大咯血是围手术期具有时间紧迫性的气道急症,其相关死亡率超过 50%。围手术期咯血的病因包括操作并发症、凝血功能障碍、恶性肿瘤、慢性肺部疾病、感染、左侧心脏疾病、肺血管疾病和自身免疫性疾病。需要快速、协调的多学科反应来确保气道安全、隔离肺部、确保充足的氧合和通气、确定潜在病因,并启动特定的全身、支气管镜、血管内或手术治疗。本文综述了围手术期大咯血的病因、病理生理学以及处理和干预方法。

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