Weiler R, Schütte M
Cell Tissue Res. 1985;241(2):373-82. doi: 10.1007/BF00217183.
Using immunocytochemical methods, we have been able to demonstrate serotonin-like immunoreactivity (SLI) in amacrine and bipolar cells of the turtle retina. Inhibition of monoamine oxidase with pargyline drastically increases the amount of 5-hydroxytryptamine within both cell types. The indoleamine 6-hydroxytryptamine is taken up by both cell types and both types are destroyed within 10 days following intraocular injection of 5,7-dihydroxytryptamine. Increasing the external potassium concentration induces release of serotonin in both cell types. Our data support the idea that these neurons use serotonin during neuronal processing. Morphologically, amacrine and bipolar cells with SLI can be subdivided into two and three subclasses, respectively, based on their ramification pattern within the inner plexiform layer. A comparison of the morphological data with those of intracellularly stained amacrine and bipolar cells suggests that all bipolar cells with SLI are center-hyperpolarizing cells and all amacrine cells center-depolarizing cells.
运用免疫细胞化学方法，我们得以在乌龟视网膜的无长突细胞和双极细胞中证实5-羟色胺样免疫反应性（SLI）。用优降宁抑制单胺氧化酶可显著增加这两种细胞类型内5-羟色胺的含量。吲哚胺6-羟色胺被这两种细胞类型摄取，并且在眼内注射5,7-二羟色胺后的10天内这两种细胞类型都会被破坏。提高细胞外钾离子浓度会诱导这两种细胞类型释放5-羟色胺。我们的数据支持这样一种观点，即这些神经元在神经处理过程中利用5-羟色胺。在形态学上，具有SLI的无长突细胞和双极细胞可分别根据它们在内网状层中的分支模式细分为两个和三个亚类。将形态学数据与细胞内染色的无长突细胞和双极细胞的数据进行比较表明，所有具有SLI的双极细胞都是中心超极化细胞，所有无长突细胞都是中心去极化细胞。
