Gonzalez J P, Fiset P, Georges A J, Saluzzo J F, Wisseman C L
Bull Soc Pathol Exot Filiales. 1985;78(2):153-6.
A serosurvey for evidence of human rickettsial infections was carried out in the Republic of Central Africa on 144 sera by indirect immunofluorescence (IIF) and microagglutination tests (MA). There was no serological evidence of epidemic typhus and only two sera were positive for murine typhus. Approximately 15% of the surveyed population was serologically positive by MA for R. conorii antibodies. However, 48% of this population had spotted fever group antibodies as detected by IIF but were negative in MA for R. conorii, R. rickettsii and R. akari antibodies. These sera with high titers in IIF and negative in MA lead us to believe that in Central Africa there are rickettsiae pathogenic for man that are related to the Spotted Fever group and are yet to be identified.
在中非共和国，采用间接免疫荧光法（IIF）和微量凝集试验（MA）对144份血清进行了人体立克次体感染证据的血清学调查。没有流行性斑疹伤寒的血清学证据，只有两份血清鼠型斑疹伤寒呈阳性。通过MA检测，约15%的受调查人群抗康氏立克次体抗体血清学呈阳性。然而，通过IIF检测，该人群中有48%具有斑点热群抗体，但在MA检测中，抗康氏立克次体、抗立氏立克次体和抗小蛛立克次体抗体呈阴性。这些IIF检测中滴度高而MA检测呈阴性的血清使我们相信，在中非存在与斑点热群相关的、对人类致病但尚未被鉴定的立克次体。
