Department of Medicinal Botanicals and Foods on Health Applications, Da-Yeh University, Changhua 515006, Taiwan (R.O.C.).
Department of Medicinal Botanicals and Foods on Health Applications, Da-Yeh University, Changhua 515006, Taiwan (R.O.C.); Department of Superintendent office/Secretary office, Chung Shan Medical University Hospital Taichung 40201, Taiwan (R.O.C.).
Int J Med Mushrooms. 2024;26(8):59-73. doi: 10.1615/IntJMedMushrooms.2024054150.
Cordyceps militaris, a medicinal fungus rich in cordycepin, shows promise in treating diseases such as cancer, respiratory issues, and COVID-19. This study examines the impact of different Taiwanese rice varieties on its solid-state fermentation, focusing on optimizing cordycepin production. The results indicated that the cordycepin yield was indeed affected by the type of rice used. In terms of the fruiting bodies, germ rice resulted in the highest yield (13.1 ± 0.36 mg/g), followed by brown rice (11.9 ± 0.26 mg/g). In the rice culture medium (RCM), brown rice led to the highest yield (4.77 ± 0.06 mg/g). Using gas chromatography-mass spectrometry and untargeted metabolomics, the study identifies four key volatile components linked to cordycepin, providing insights into developing functional rice porridge products. These findings are significant for advancing cordycepin mass production and offering dietary options for older individuals.
蛹虫草是一种富含蛹虫草素的药用真菌，在治疗癌症、呼吸系统疾病和 COVID-19 等疾病方面显示出潜力。本研究探讨了不同台湾大米品种对其固态发酵的影响，重点是优化蛹虫草素的生产。结果表明，大米的种类确实会影响蛹虫草素的产量。就子实体而言，糙米饭的产量最高（13.1±0.36mg/g），其次是糙米（11.9±0.26mg/g）。在大米培养基（RCM）中，糙米的产量最高（4.77±0.06mg/g）。通过气相色谱-质谱联用和非靶向代谢组学，该研究鉴定出与蛹虫草素相关的四个关键挥发性成分，为开发功能性大米粥产品提供了思路。这些发现对推进蛹虫草素的大规模生产和为老年人提供饮食选择具有重要意义。
