Department of Ophthalmology, Goethe-University, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
Graefes Arch Clin Exp Ophthalmol. 2024 Nov;262(11):3693-3700. doi: 10.1007/s00417-024-06557-z. Epub 2024 Jul 5.
To evaluate formulas for intraocular lens (IOL) calculation in children undergoing lens extraction and IOL implantation.
Retrospective, consecutive case series at the Department of Ophthalmology, Goethe University Frankfurt, Germany. We included eyes that received lens extraction and IOL implantation (SN60AT, Alcon, Fort Worth, TX) due to congenital or juvenile cataract. Preoperative assessments included biometry (IOLMaster 500/700, Carl Zeiss Meditec, Germany). To evaluate the measurements, we compared the mean prediction error (MPE), mean and median absolute prediction error (MAE, MedAE) of six different formulas, and number of eyes within ± 0.5, ± 1.0, ± 2.0D of target refraction. Postoperative spherical equivalent was measured by retinoscopy 4-12 weeks after surgery.
66 eyes matched our inclusion criteria with a mean age of 6.3 years ± 3.2. MedAE was lowest in SRK/T (0.55D ± 1.08) followed by Holladay I (0.75D ± 1.00), EVO 2.0 (0.80D ± 0.89), Barrett Universal II (BUII, 0.86D ± 1.00), Hoffer Q (0.97 D ± 0.94), and Haigis (1.10D ± 0.95). Regarding eyes within ± 0.5D SRK/T (45.5.%, 30 eyes) performed best, followed by Holladay I (36.4%, 24 eyes), EVO 2.0 and BUII (each 34.8%, 23 eyes). There was a myopic shift seen in all formulas (MPE: -0.21 to -0.90D).
Using modern formulas, or even AI formulas, for IOL calculation in children's eyes does barely improve predictability of the postoperative refraction. A myopic shift can be found for all formulas. However, specific formulas like SRK/T seem to better anticipate this.
评估儿童白内障晶状体切除和人工晶状体植入术中人工晶状体（IOL）计算公式。
德国法兰克福歌德大学眼科系的回顾性连续病例系列。我们纳入了因先天性或幼年性白内障而接受晶状体切除和人工晶状体植入（SN60AT，Alcon，德克萨斯州沃思堡）的眼睛。术前评估包括生物测量（IOLMaster 500/700，卡尔蔡司医疗技术公司，德国）。为了评估测量结果，我们比较了 6 种不同公式的平均预测误差（MPE）、平均和中位数绝对预测误差（MAE、MedAE），以及屈光度在±0.5、±1.0、±2.0D 以内的眼数。术后 4-12 周通过视网膜检影术测量术后等效球镜。
66 只眼睛符合纳入标准，平均年龄为 6.3 岁±3.2 岁。SRK/T 的 MedAE 最低（0.55D±1.08），其次是 Holladay I（0.75D±1.00）、EVO 2.0（0.80D±0.89）、Barrett Universal II（BUII，0.86D±1.00）、Hoffer Q（0.97 D±0.94）和 Haigis（1.10D±0.95）。对于屈光度在±0.5D 以内的眼，SRK/T（45.5%，30 只眼）的效果最好，其次是 Holladay I（36.4%，24 只眼）、EVO 2.0 和 BUII（各 34.8%，23 只眼）。所有公式均存在近视漂移（MPE：-0.21 至-0.90D）。
使用现代公式，甚至 AI 公式，对儿童眼的 IOL 计算几乎不能提高术后屈光度的预测能力。所有公式都可以发现近视漂移。然而，像 SRK/T 这样的特定公式似乎可以更好地预测这一点。
