（+）-矢车菊素-3对慢性活动性肝炎的影响：一项双盲对照试验。
Effect of (+)-cyanidanol-3 on chronic active hepatitis: a double blind controlled trial.
作者信息
Bar-Meir S, Halpern Z, Gutman M, Shpirer Z, Baratz M, Bass D
出版信息
Gut. 1985 Sep;26(9):975-9. doi: 10.1136/gut.26.9.975.
Abstract
Forty patients with biopsy proven chronic active hepatitis were studied, 22 received (+)-cyanidanol-3 in a dose of 3 g daily and 18 placebo. Side effects related to cyanidanol were fever (four patients), haemolysis (one patient) and urticaria (one patient). All side effects subsided on discontinuation of the medication. Cyanidanol had an effect no better than placebo on symptoms, laboratory tests, and histological findings on liver biopsy.
摘要
对40例经活检证实为慢性活动性肝炎的患者进行了研究，其中22例患者每日服用3克（+）-氰定醇-3，18例服用安慰剂。与氰定醇相关的副作用有发热（4例患者）、溶血（1例患者）和荨麻疹（1例患者）。停药后所有副作用均消退。氰定醇在症状、实验室检查及肝活检组织学结果方面的效果并不比安慰剂更好。
相似文献
1
Effect of (+)-cyanidanol-3 on chronic active hepatitis: a double blind controlled trial.（+）-矢车菊素-3对慢性活动性肝炎的影响：一项双盲对照试验。
Gut. 1985 Sep;26(9):975-9. doi: 10.1136/gut.26.9.975.
2
Therapeutic effect of (+)-cyanidanol-3 in toxic alcoholic liver disease and in chronic active hepatitis.（+）- 氰定醇 -3 对中毒性酒精性肝病和慢性活动性肝炎的治疗作用。
Acta Physiol Hung. 1984;64(3-4):455-60.
3
Treatment of acute viral hepatitis with (+)-cyanidanol-3.用（+）-儿茶素-3治疗急性病毒性肝炎。
Lancet. 1977 Dec 3;2(8049):1153-5. doi: 10.1016/s0140-6736(77)91540-9.
4
Cianidanol therapy for HBe-antigen-positive chronic hepatitis: a multicentre, double-blind study.西尼达醇治疗HBe抗原阳性慢性肝炎：一项多中心、双盲研究。
Liver. 1986 Feb;6(1):35-44. doi: 10.1111/j.1600-0676.1986.tb00266.x.
5
6
[A double-blind clinical study of the effect of a new molecule (+)-cyanidanol-3 on the course of the clinical symptoms and biological parameters of viral hepatitis].
Minerva Dietol Gastroenterol. 1977 Oct-Dec;23(4):307-12.
7
8
Treatment of alcohol-related liver disease with (+)-cyanidanol-3: a randomised double-blind trial.用（+）-矢车菊素-3治疗酒精性肝病：一项随机双盲试验。
Gut. 1980 Nov;21(11):965-9. doi: 10.1136/gut.21.11.965.
9
[Effect of (+)-cyanidanol-3 in the treatment of chronic active hepatitis (author's transl)].
Gastroenterol Clin Biol. 1981 Mar;5(3):314-23.
10
(+)-Cyanidanol-3 in the treatment of acute viral hepatitis: a randomized controlled trial.
Hepatology. 1984 Mar-Apr;4(2):331-5. doi: 10.1002/hep.1840040226.
引用本文的文献
1
Historical treatment of chronic hepatitis B and chronic hepatitis C.慢性乙型肝炎和慢性丙型肝炎的既往治疗情况。
Gut. 1993;34(2 Suppl):S69-73. doi: 10.1136/gut.34.2_suppl.s69.
2
Trial of (+)-cyanidanol-3 in patients with hepatitis B chronic liver disease.（+）-氰定醇-3治疗慢性乙型肝炎患者的试验。
J R Soc Med. 1986 Aug;79(8):460-1. doi: 10.1177/014107688607900809.
本文引用的文献
1
(+)-Cyanidanol-3 in the treatment of acute viral hepatitis: a randomized controlled trial.
Hepatology. 1984 Mar-Apr;4(2):331-5. doi: 10.1002/hep.1840040226.
2
3
The effect of (+)-catechin on the hepatic level of ATP and the lipid content of liver during experimental steatosis.（+）-儿茶素对实验性脂肪变性期间肝脏ATP水平及肝脏脂质含量的影响。
Biochem Pharmacol. 1972 Feb 15;21(4):594-600. doi: 10.1016/0006-2952(72)90338-3.
4
Treatment of acute viral hepatitis with (+)-cyanidanol-3.用（+）-儿茶素-3治疗急性病毒性肝炎。
Lancet. 1977 Dec 3;2(8049):1153-5. doi: 10.1016/s0140-6736(77)91540-9.
Zotero 插件