Key Laboratory of Shaanxi Administration of Traditional Chinese Medicine for TCM Compatibility, and Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, Shaanxi University of Chinese Medicine, Xianyang, 712046, Shaanxi Province, China.
Key Laboratory of Shaanxi Administration of Traditional Chinese Medicine for TCM Compatibility, and Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, Shaanxi University of Chinese Medicine, Xianyang, 712046, Shaanxi Province, China.
J Ethnopharmacol. 2025 Jan 10;336:118522. doi: 10.1016/j.jep.2024.118522. Epub 2024 Jul 4.
Labisia pumila (Blume) Fern.-Vill, also known as Kacip Fatimah, is a traditional medicinal herb common throughout Southeast Asia. It is primarily used to facilitate childbirth and postpartum recovery in women. Additionally, it can also be used to treat dysentery, rheumatism, gonorrhea, and as an anti-flatulent.
This article aims to provide a comprehensive review of the traditional uses, botany, cultivation, phytochemistry, pharmacological effects, practical applications, and potential uses of L. pumila (LP). Furthermore, we also explore the safety of this plant and its potential prospects for application.
The keywords "Labisia pumila," "Kacip Fatimah," and "Marantodes pumilum" were used to collect relevant information through electronic searches (including Elsevier, PubMed, Google Scholar, Baidu Scholar, CNKI, ScienceDirect, and Web of Science).
This review summarizes 102 chemical components from different parts of the plant, including flavonoids, phenolic acids, saponins, and other chemical components. In addition, we also address the associated cultivation conditions, traditional uses, pharmacological effects and toxicity. A large number of reports indicate that LP has various pharmacological effects such as antioxidant, phytoestrogenic, anti-inflammtory, antimicrobial, anti-osteoporosis and anti-obesity properties. These results provide valuable references for future research on LP. In addition, LP is also a potential medicinal and edible plant, and is currently sold on the market as a dietary supplement.
LP is a renowned traditional ethnic medicine with numerous pharmacological activities attributed to its bioactive components. Therefore, isolation and identification of the chemical components in LP can be a focus of our future research. Current studies have focused only on the effects of LP on estrogen deficiency-related diseases in women and bone diseases. There is no scientific evidence for other traditional uses. Therefore, it is important to further explore its pharmacological activities and fill the research gaps related to other traditional uses. Furthermore, research on its safety should be expanded to prepare clinical applications.
Labisia pumila（Blume）Fern.-Vill，也被称为 Kacip Fatimah，是东南亚常见的传统药用植物。它主要用于促进妇女分娩和产后恢复。此外，它还可用于治疗痢疾、风湿、淋病和作为消胀剂。
本文旨在对 L. pumila（LP）的传统用途、植物学、栽培、植物化学、药理作用、实际应用和潜在用途进行全面综述。此外，我们还探讨了该植物的安全性及其潜在的应用前景。
使用关键词“Labisia pumila”、“Kacip Fatimah”和“Marantodes pumilum”通过电子搜索（包括 Elsevier、PubMed、Google Scholar、百度学术、CNKI、ScienceDirect 和 Web of Science）收集相关信息。
本综述总结了来自植物不同部位的 102 种化学成分，包括黄酮类、酚酸类、皂苷类等化学成分。此外，我们还介绍了相关的栽培条件、传统用途、药理作用和毒性。大量报道表明，LP 具有抗氧化、植物雌激素、抗炎、抗菌、抗骨质疏松和抗肥胖等多种药理作用。这些结果为 LP 的进一步研究提供了有价值的参考。此外，LP 也是一种有潜力的药用和食用植物，目前作为膳食补充剂在市场上销售。
LP 是一种著名的传统民族药物，具有多种药理活性，这与其生物活性成分有关。因此，LP 中化学成分的分离和鉴定可以成为我们未来研究的重点。目前的研究仅集中在 LP 对女性雌激素缺乏相关疾病和骨骼疾病的影响上。对于其他传统用途，没有科学证据。因此，有必要进一步探讨其药理活性，填补其他传统用途的研究空白。此外，还应扩大其安全性研究，为临床应用做好准备。
