Department of Internal Medicine, Kampala International University Western Campus, Ishaka, Uganda.
College of Health Sciences, School of Public Health, Makerere University, Kampala, Uganda.
Curr Probl Cardiol. 2024 Sep;49(9):102741. doi: 10.1016/j.cpcardiol.2024.102741. Epub 2024 Jul 6.
In Uganda, hypertension is a rapidly increasing non-communicable disease with high morbidity and mortality, leading to complications such as renal failure, heart failure, stroke, and myocardial infarctions. This study aimed to determine the factors associated with left ventricular hypertrophy (LVH) among hypertensive patients at Jinja Regional Referral Hospital. A cross-sectional study was conducted among 323 participants using convenience sampling, the study utilized structured questionnaires and data was analyzed using STATA. Results indicated that factors independently associated with LVH included alcohol consumption (aOR 0.26, 95%CI 0.10-0.70, P=0.007), lack of physical exercise (aOR 0.47, 95%CI 0.23-0.94, P=0.033), Low medication adherence (aOR 0.31, 95%CI 0.13-0.71, P=0.006)., female participants who had waist-hip-ratio >0.80 (aOR 3.70, 95%CI 1.18-11.64, P=0.025), diastolic blood pressure of 100 - 109 mmHg (aOR 4.58, 95%CI 1.65-12.74, P=0.004) and diastolic blood pressure of ≤89 mmHg (aOR 3.03, 95%CI 1.03-8.89, P=0.044). The study highlights the need for better management of hypertension and lifestyle modifications to reduce LVH prevalence.
在乌干达,高血压是一种发病率和死亡率都很高的快速增长的非传染性疾病,可导致肾衰竭、心力衰竭、中风和心肌梗死等并发症。本研究旨在确定金贾地区转诊医院高血压患者左心室肥厚(LVH)的相关因素。采用便利抽样法,对 323 名参与者进行了横断面研究,研究采用了结构化问卷,数据采用 STATA 进行分析。结果表明,与 LVH 独立相关的因素包括饮酒(aOR 0.26,95%CI 0.10-0.70,P=0.007)、缺乏体育锻炼(aOR 0.47,95%CI 0.23-0.94,P=0.033)、低药物依从性(aOR 0.31,95%CI 0.13-0.71,P=0.006)。女性参与者中,腰围臀围比>0.80(aOR 3.70,95%CI 1.18-11.64,P=0.025)、舒张压为 100-109mmHg(aOR 4.58,95%CI 1.65-12.74,P=0.004)和舒张压≤89mmHg(aOR 3.03,95%CI 1.03-8.89,P=0.044)的患者LVH 风险更高。该研究强调了需要更好地管理高血压和进行生活方式改变,以降低 LVH 的患病率。