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机器人辅助左胰切除术联合肾周组织切除及左肾上腺切除术(后入路)治疗毗邻肾上腺的胰腺导管腺癌

Robotic Left Pancreatectomy with Perirenal Tissue Excision and Left Adrenalectomy (Posterior Ramps) for Pancreatic Ductal Adenocarcinoma Abutting the Adrenal Gland.

作者信息

Giannone Fabio, Ligurgo Oronzo, Kock Arne, Barlerin Valere, Cherkaoui Zineb, Pessaux Patrick

机构信息

Department of Visceral and Digestive Surgery, University Hospital of Strasbourg, Strasbourg, France.

Inserm, Institut de Recherche sur les Maladies Virales et Hépatiques, Université de Strasbourg, U1110, Strasbourg, France.

出版信息

Ann Surg Oncol. 2024 Sep;31(9):6195-6196. doi: 10.1245/s10434-024-15414-6. Epub 2024 Jul 7.

Abstract

BACKGROUND

Radical antegrade modular pancreato-splenectomy (RAMPS) has been largely described in left-sided pancreatic cancers.1.J Hepato-Biliary-Pancreat Sci 29:1156-1165 Its prognostic advantage is not clear, although a theoretical improvement in R0 resection rate has been shown.2.J Am Coll Surg 204:244-249 Furthermore, RAMPS is usually carried out without adrenal gland removal, the so-called anterior RAMPS, while extending the resection to the adrenal plane could impair perioperative outcomes.3.HPB 25:311-319 METHODS: A 40 mm pancreatic ductal adenocarcinoma (PDAC) was found in a 70-year-old patient. Tumor infiltrates the adrenal gland and a robotic posterior RAMPS was indicated.

RESULTS

After sectioning the splenic vessels and the pancreatic neck, the dissection was directed vertically in a sagittal plane along the left border of the superior mesenteric artery to identify the left renal vein. Our dissection plane was then directed on a caudo-cranial axis, after identification of the left renal artery and below the adrenal gland. The resection was also delimitated medially by the left borders of the superior mesenteric artery and the aorta, and posteriorly by the renal parenchyma. Postoperative course was marked by a biochemical leak. The patient was discharged on postoperative day (POD) 5 and the drain removed at POD 18. Pathological examination confirmed a pT2N2 PDAC with negative margins, with 4/18 positive nodes.

CONCLUSIONS

The robotic platform is routinely employed in pancreatic surgery. Thanks to its increased degree of movement, its dexterity, and the magnification, this approach can help surgeons with vascular identification and control, in performing extended lymphadenectomies, and finding the correct planes of dissection. All these elements are crucial in a well-performed posterior RAMPS.

摘要

背景

根治性顺行模块化胰脾切除术(RAMPS)在左侧胰腺癌中已有大量描述。1.《肝脏-胆道-胰腺科学杂志》29:1156 - 1165 其预后优势尚不清楚,尽管已显示出R0切除率在理论上有所提高。2.《美国外科医师学会杂志》204:244 - 249 此外,RAMPS通常在不切除肾上腺的情况下进行,即所谓的前路RAMPS,而将切除范围扩展至肾上腺平面可能会损害围手术期结局。3.《肝脏胰腺胆管杂志》25:311 - 319 方法:在一名70岁患者中发现了一个40毫米的胰腺导管腺癌(PDAC)。肿瘤侵犯肾上腺,遂行机器人辅助后路RAMPS。

结果

切断脾血管和胰腺颈部后,沿肠系膜上动脉左缘在矢状面垂直进行解剖以识别左肾静脉。在识别左肾动脉并在肾上腺下方后,我们的解剖平面沿尾颅轴方向。切除范围在内侧由肠系膜上动脉和主动脉的左缘界定,后方由肾实质界定。术后过程以生化漏为特征。患者于术后第5天出院,术后第18天拔除引流管。病理检查证实为pT2N2 PDAC,切缘阴性,18个淋巴结中有4个阳性。

结论

机器人平台常用于胰腺手术。由于其更大的活动度、灵活性和放大倍数,这种方法有助于外科医生识别和控制血管、进行扩大的淋巴结清扫以及找到正确的解剖平面。所有这些因素在成功实施后路RAMPS中都至关重要。

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