Barat Shahnaz, Shahrokhi Shirin, Mirtabar Seyyedeh Mahboubeh, Kheirkhah Farzan, Basirat Zahra, Shirafkan Hoda, Hamidia Angela, Hosseini Davood, Pahlavan Zeynab, Esmaeilzadeh Sedigheh, Buzari Zinatosadat, Zeynalzadeh Mahtab, Yazdani Charati Shahla, Ghanbarpour Azita, Shafizadeh Fatemeh, Adnani Mahsima, Amirkhanloo Fatemeh, Mollaalipour Maedeh, Chale Kani Atiyeh, Amiri Mania, Khazaei Razieh, Mehdinia Seyedeh Shabnam, Basirat Fatemeh, Hamzehpour Romina, Khademi Asieh, Azizi Alireza, Nasiri-Amiri Fatemeh, Fateri Nooshin, Zarinkamar Banafshe, Aligoltabar Sajedeh, Faramarzi Mahbobeh
Department of Obstetrics and Gynecology, Infertility and Reproductive Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Clinical Psychology, Student Research Committee, Behshahr Azad University, Behshahr, Iran.
Int J Fertil Steril. 2024 Jun 9;18(3):271-277. doi: 10.22074/ijfs.2023.1983056.1412.
Prenatal and postnatal depression (PND) is associated with adverse outcomes for mother, fetus, and child. The aim of study was to examine the prevalence and risk factors of prenatal and postnatal depressive symptoms.
This was a cross-sectional and hospital-based survey of 2305 pregnant women and post-partum women (18-48 years) that was registered in the Babol Pregnancy Mental Health Registry (BPMHR) database from June 2020 to March 2021. Two questionnaires, including demographics and depression, were analyzed in this study. Also, the Edinburg Postnatal Depression Scale (EPDS) was used to assess the depressive symptoms. Independent t test and the analysis of variance were used to compare the means. Multiple logistic regressions were used to determine risk factors for depressive symptoms.
According to the EPDS scale, the prevalence of depressive symptoms was 19.8% in the pregnant woman group in comparison with the postpartum period (11.6%). Risk factors for antenatal depressive symptoms were parity (women with parity ≥ 4 vs. 1 parity, ß=1.808, P=0.020), two groups of gestational age (gestational age ≤12 weeks vs. 28 weeks, ß=1.562 P=0.030) as well as (gestational age 21-27 weeks vs. 28 weeks (ß=1.586, P=0.033), and high-risk pregnancy (high-risk vs. low-risk pregnancy, ß=1.457, P=0.003). For postnatal depressive symptoms, none of the factors were a significant risk.
Prenatal and postnatal depressive symptoms should be screened, particularly for women in the first and second trimesters, with high parity, and those with a high-risk pregnancy, as recommended by the present study.
产前和产后抑郁症（PND）与母亲、胎儿和儿童的不良结局相关。本研究的目的是调查产前和产后抑郁症状的患病率及危险因素。
这是一项基于医院的横断面调查，对2020年6月至2021年3月在巴博尔妊娠心理健康登记处（BPMHR）数据库中登记的2305名孕妇和产后妇女（18 - 48岁）进行了调查。本研究分析了两份问卷，包括人口统计学和抑郁症相关内容。此外，使用爱丁堡产后抑郁量表（EPDS）评估抑郁症状。采用独立t检验和方差分析比较均值。使用多元逻辑回归确定抑郁症状的危险因素。
根据EPDS量表，孕妇组抑郁症状的患病率为19.8%，产后组为11.6%。产前抑郁症状的危险因素包括产次（产次≥4的女性与产次为1的女性相比，ß = 1.808，P = 0.020）、两组孕周（孕周≤12周与28周相比，ß = 1.562，P = 0.030）以及（孕周21 - 27周与28周相比，ß = 1.586，P = 0.033），还有高危妊娠（高危妊娠与低危妊娠相比，ß = 1.457，P = 0.003）。对于产后抑郁症状，没有因素是显著的危险因素。
应按照本研究的建议，对产前和产后抑郁症状进行筛查，特别是对孕早期和孕中期、产次高以及高危妊娠的女性。
