Adeniyi Faith I, John-Akinola Yetunde O, Oluwasanu Mojisola M
Department of Health Promotion and Education, Faculty of Public Health, College of Medicine, University of Ibadan, Nigeria.
Niger Med J. 2023 Jul 2;64(3):352-364. eCollection 2023 May-Jun.
Human papillomavirus (HPV) is a very common sexually transmitted infection responsible for some cancers including cervical cancer. Despite nearly half of the Nigerian population being at risk (women <25), vaccination uptake against the infection is still less than 5%.
This cross-sectional descriptive survey was conducted using a multi-stage sampling technique. A semi-structured questionnaire was administered to 300 in-school adolescents aged 15-19 years, across 15 private and public secondary schools in Ibadan-North and Ibadan North-West of Oyo State, whose parents gave consent. The data was analysed using descriptive and inferential statistics in SPSS v21. Cronbach's alpha coefficient was used to measure internal consistency reliability while categorical tables were compared using chi-square and regression analysis with a p-value <0.05.
The mean age of respondents was 15.8 ± 0.84 years. Half of them were females (52.3%) and also attended private schools (56.3%). Very few of the respondents had heard about HPV (21.0%) and HPV vaccine (12.7%), however, more than half had heard about cervical cancer (55.3%). Few respondents had good knowledge (11.0%) and positive perception (27.0%) of HPV, cervical cancer and HPV vaccine. The major source of information was social media (46.2%). Half of the respondents reported intention to take the vaccine if recommended by their family doctor (56.3%) and if given parental approval (52.0%), however, many (60.7%) were concerned about the vaccine's side effects.
Findings show that parents and health workers influence adolescents' HPV vaccination uptake. The study thus recommends the prioritization of parental involvement in HPV vaccination. Parents and health workers should therefore be targeted as key stakeholders in driving the awareness of HPV and uptake of HPV vaccine among adolescents.
人乳头瘤病毒（HPV）是一种非常常见的性传播感染，可引发包括宫颈癌在内的某些癌症。尽管近一半的尼日利亚人口面临感染风险（25岁以下女性），但针对该感染的疫苗接种率仍低于5%。
本横断面描述性调查采用多阶段抽样技术。对奥约州伊巴丹北部和伊巴丹西北部15所私立和公立中学的300名15至19岁在校青少年进行了半结构化问卷调查，这些青少年的父母已给予同意。使用SPSS v21中的描述性和推断性统计方法对数据进行分析。Cronbach's alpha系数用于测量内部一致性信度，分类表则使用卡方检验进行比较，并进行p值<0.05的回归分析。
受访者的平均年龄为15.8±0.84岁。其中一半为女性（52.3%），且就读于私立学校（56.3%）。很少有受访者听说过人乳头瘤病毒（21.0%）和人乳头瘤病毒疫苗（12.7%），然而，超过一半的人听说过宫颈癌（55.3%）。很少有受访者对人乳头瘤病毒、宫颈癌和人乳头瘤病毒疫苗有良好的了解（11.0%）和积极的认知（27.0%）。主要的信息来源是社交媒体（46.2%）。一半的受访者表示，如果家庭医生推荐（56.3%）且获得父母批准（52.0%），他们打算接种疫苗，然而，许多人（60.7%）担心疫苗的副作用。
研究结果表明，父母和卫生工作者会影响青少年的人乳头瘤病毒疫苗接种率。因此，该研究建议优先让父母参与人乳头瘤病毒疫苗接种。因此，应将父母和卫生工作者作为关键利益相关者，以提高青少年对人乳头瘤病毒的认识并促进其人乳头瘤病毒疫苗接种。
