Nakamura Itaru, Kobayashi Takehito, Fukuzawa Masakatsu, Komori Kohji, Yamaguchi Tetsuo
Department of Infection Prevention and Control, Tokyo Medical University Hospital, Japan.
Department of Gastroenterology and Hepatology, Tokyo Medical University Hospital, Japan.
IDCases. 2024 Jun 7;37:e02010. doi: 10.1016/j.idcr.2024.e02010. eCollection 2024.
This case report demonstrates successful treatment outcomes without recurrence using fosfomycin for cellulitis with bacteremia caused by resistant to macrolides, fluoroquinolones, and tetracyclines in agammaglobulinemia and bronchiectasis. Whole-genome sequencing indicated the presence of ST137 harboring and , with mutations in the 23S rRNA and genes.
本病例报告显示,在无丙种球蛋白血症和支气管扩张症患者中,对于由对大环内酯类、氟喹诺酮类和四环素类耐药的细菌引起的蜂窝织炎合并菌血症,使用磷霉素治疗取得了成功的治疗效果且无复发。全基因组测序表明存在携带[具体基因]和[具体基因]的ST137,23S rRNA和[具体基因]有突变。