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在阿根廷一家屠宰场中鉴定出的[具体内容缺失]的流行情况及抗菌药物耐药性 。 (因原文部分关键信息缺失,翻译可能不太完整准确,你可补充完整原文后继续向我提问)

Prevalence and antimicrobial resistance of and identified in a slaughterhouse in Argentina.

作者信息

Schreyer Mariana E, Olivero Carolina R, Rossler Eugenia, Soto Lorena P, Frizzo Laureano S, Zimmermann Jorge A, Signorini Marcelo L, Virginia Zbrun M

机构信息

Laboratory of Food Analysis, Institute of Veterinary Science (ICiVet Litoral), National University of the Litoral, National Council of Scientific and Technical Research (UNL/CONICET), 2805 Kreder St., S3080HOF, Esperanza, Province of Santa Fe, Argentina.

Department of Public Health, Faculty of Veterinary Science - Litoral National University, 2805 Kreder St., S3080HOF, Esperanza, Province of Santa Fe, Argentina.

出版信息

Curr Res Food Sci. 2022 Mar 17;5:590-597. doi: 10.1016/j.crfs.2022.03.005. eCollection 2022.

Abstract

The aim of this study was to evaluate the percentage of ( and ) from samples collected at the slaughterhouse to describe the prevalence of resistance to selected antimicrobials, and to characterize the genetic determinants. In total, from 333 samples analyzed, 31% were positive for More positive samples were detected before the chiller (46%) than after the chiller (16%). (59%) was more prevalent than (41%). Antimicrobial resistance differences between and were found (p < 0.001). Multidrug resistance was found in 72% of isolates and 69% of isolates (p < 0.001). Most isolates (57%) had the three genes of the efflux pump. The gene and resistance-associated point mutations within both the and 23S rRNA genes were detected in 100% of isolates. On the other hand, only had more prevalence of the gene than (p < 0.001), and most of the isolates (70-80%) had the and point mutation. These results could contribute to knowledge about the status of thermotolerant resistant to antimicrobials isolated from food animals in Argentina and to develop an antimicrobial resistance surveillance system.

摘要

本研究的目的是评估从屠宰场采集的样本中(和)的百分比,以描述对选定抗菌药物的耐药性流行情况,并鉴定遗传决定因素。总共分析了333个样本,其中31%的样本对呈阳性。在预冷器之前检测到的阳性样本(46%)比预冷器之后(16%)更多。(59%)比(41%)更普遍。和之间发现了抗菌药物耐药性差异(p<0.001)。在72%的分离株和69%的分离株中发现了多重耐药性(p<0.001)。大多数分离株(57%)具有外排泵的三个基因。在100%的分离株中检测到基因以及和23S rRNA基因内的耐药相关点突变。另一方面,仅在基因的流行率上比更高(p<0.001),并且大多数分离株(70 - 80%)具有和点突变。这些结果有助于了解阿根廷从食用动物中分离出的耐热对抗菌药物的耐药状况,并有助于建立抗菌药物耐药性监测系统。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28aa/8943338/ea1305e56ade/ga1.jpg

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