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小儿尸体肾移植到成人身上。

Pediatric cadaver kidney transplants into adults.

作者信息

Barry J M, Norman D J, Bennett W M

出版信息

J Urol. 1985 Oct;134(4):651-3. doi: 10.1016/s0022-5347(17)47367-8.

DOI:10.1016/s0022-5347(17)47367-8
PMID:3897580
Abstract

During a 5-year period 77 adults received single kidney cadaver transplants from donors 16 months to 16 years old. Cyclosporin immunosuppression was not used. Three recipients had ischemic ureteral complications, 1 of which resulted in allograft loss. Of the kidney grafts 34 were from donors 8 years old or younger, and comparison of renal function was made with the 43 adult recipients of cadaver kidneys from older children. The mean 1-month serum creatinine nadir was significantly higher in the recipients of kidneys from the younger children (2.6 plus or minus 1.6 versus 1.9 plus or minus 0.8 mg./per dl.). There were no statistically significant differences in 1-week dialysis requirement, 1-month kidney graft function or actuarial kidney graft survivals and serum creatinine levels at 3, 6, 12 and 24 months after grafting. Cadaver kidneys from young donors can be transplanted successfully into adults.

摘要

在5年期间,77名成年人接受了来自16个月至16岁供体的单肾尸体移植。未使用环孢素免疫抑制。3名受者出现缺血性输尿管并发症,其中1例导致移植肾丧失。34个肾移植来自8岁及以下的供体,并将其肾功能与43名接受大龄儿童尸体肾移植的成年受者进行了比较。较年幼儿童供肾受者的1个月血清肌酐最低点显著更高(2.6±1.6对1.9±0.8mg/每分升)。在移植后1周透析需求、1个月移植肾功能、精算移植肾存活率以及3、6、12和24个月时的血清肌酐水平方面,无统计学显著差异。年幼供体的尸体肾可成功移植给成年人。

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