Fernández O, Montalbán X, Agüera E, Aladro Y, Alonso A, Arroyo R, Brieva L, Calles C, Costa-Frossard L, Eichau S, García-Domínguez J M, Hernández M A, Landete L, Llaneza M, Llufriu S, Meca-Lallana J E, Meca-Lallana V, Moral E, Prieto J M, Ramió-Torrentà Ll, Téllez N, Romero-Pinel L, Vilaseca A, Rodríguez-Antigüedad A
Universidad de Málaga, Málaga, España.
Instituto de Investigación Biomédica de Málaga. IBIMA, Málaga, España.
Rev Neurol. 2024 Jul 16;79(2):51-66. doi: 10.33588/rn.7902.2024174.
The XVI Post-ECTRIMS meeting was held in Seville on 20 and 21 October 2023, where expert neurologists in multiple sclerosis (MS) summarised the main new developments presented at the ECTRIMS 2023 congress, which took place in Milan from 11 to 13 October. The aim of this article is to summarise the content presented at the Post-ECTRIMS Meeting, in an article in two parts. This second part covers the health of women and elderly MS patients, new trends in the treatment of cognitive impairment, focusing particularly on meditation, neuroeducation and cognitive rehabilitation, and introduces the concept of fatigability, which has been used to a limited extent in MS. The key role of digitalization and artificial intelligence in the theoretically near future is subject to debate, along with the potential these technologies can offer. The most recent research on the various treatment algorithms and their efficacy and safety in the management of the disease is reviewed. Finally, the most relevant data for cladribine and evobrutinib are presented, as well as future therapeutic strategies currently being investigated.
第十六届ECTRIMS会后会议于2023年10月20日至21日在塞维利亚举行，多位多发性硬化症（MS）专家神经学家总结了10月11日至13日在米兰举行的2023年ECTRIMS大会上展示的主要新进展。本文旨在分两部分对ECTRIMS会后会议上展示的内容进行总结。第二部分涵盖了MS女性患者和老年患者的健康状况、认知障碍治疗的新趋势，特别关注冥想、神经教育和认知康复，并介绍了疲劳易感性的概念，该概念在MS中的应用程度有限。数字化和人工智能在理论上不远的未来的关键作用以及这些技术可能带来的潜力仍有待讨论。本文还回顾了各种治疗算法及其在疾病管理中的疗效和安全性的最新研究。最后，展示了克拉屈滨和依沃布替尼的最相关数据以及目前正在研究的未来治疗策略。
