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香港居民多环芳烃的饮食暴露。

Dietary exposure to polyaromatic hydrocarbons of the Hong Kong population.

机构信息

Food and Environmental Hygiene Department, Risk Assessment Section, Centre for Food Safety, Hong Kong, China.

Food and Environmental Hygiene Department, 43/F Queensway Government Offices, Risk Assessment Section, Centre for Food Safety, Hong Kong, China.

出版信息

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2024 Aug;41(8):969-978. doi: 10.1080/19440049.2024.2358509. Epub 2024 Jul 8.

Abstract

Polyaromatic hydrocarbons (PAHs) are ubiquitous in the environment and food. The Joint FAO/WHO Expert Committee on Food Additives concluded 13 individual PAHs are carcinogenic and genotoxic and . Food is recognized as the main source of exposure to PAHs for adult non-smokers, which contributed to more than 90% of total exposure. In this study, 300 food samples were collected in Hong Kong, analysed the levels of 16 European Union priority PAHs, the dietary exposure to these PAHs by the local adult population from these food items, and the associated health risk. The most predominant detectable PAH was chrysene (CHR) (14.4%), followed by benzo[c]fluorene (11.2%), benzo[a]anthracene (BaA) (10.6%) and benzo[b]fluoranthene (BbFA) (7.8%). The dietary exposures for average consumers of benzo[a]pyrene (BaP) and PAH4 (sum of BaP, CHR, BaA and BbFA) were 0.13-0.90 and 1.4-4.2 ng/kg bw/day respectively for lower and upper bound approaches. Cereal and its products contributed more than 50% to BaP and PAH4 for average consumers in a lower-bound approach. The margin of exposure (MOE) approach was used to assess the health risks of consumers. The calculated MOE values for both BaP and PAH4 of the average and high consumers (90th percentile) were >50,000, indicating a low concern for the health of the Hong Kong population.

摘要

多环芳烃(PAHs)普遍存在于环境和食物中。粮农组织/世界卫生组织食品添加剂联合专家委员会总结认为,13 种单独的 PAHs 具有致癌性和遗传毒性。食物被认为是成人非吸烟者接触 PAHs 的主要来源,其接触量占总接触量的 90%以上。本研究在香港采集了 300 个食品样本,分析了 16 种欧盟优先 PAHs 的水平,当地成年人群从这些食物中摄入这些 PAHs 的情况,以及相关的健康风险。最主要的可检测 PAH 是䓛(CHR)(14.4%),其次是苯并[c]荧蒽(11.2%)、苯并[a]蒽(BaA)(10.6%)和苯并[b]荧蒽(BbFA)(7.8%)。对于低和高摄入量人群,BaP 和 PAH4(BaP、CHR、BaA 和 BbFA 的总和)的平均消费者的膳食暴露量分别为 0.13-0.90 和 1.4-4.2ng/kg bw/day。对于低摄入量人群,谷类及其制品对 BaP 和 PAH4 的贡献超过 50%。采用暴露量边际评估法(MOE)评估消费者的健康风险。低和高摄入量人群(90 百分位数)的 BaP 和 PAH4 的计算 MOE 值均>50,000,表明香港人群的健康风险较低。

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