Department of Public Health, Faculty of Health Science and Technology, Rift Valley University, Ambo Campus, Ambo, Ethiopia.
Student Services Unit, Wollega University, Nekemte, Ethiopia.
PLoS One. 2024 Jul 8;19(7):e0305200. doi: 10.1371/journal.pone.0305200. eCollection 2024.
Understanding and addressing the concerns of vaccine-hesitant individuals, including those with chronic diseases, is key to increasing vaccine acceptance and uptake. However, in Ethiopia, there is limited evidence on the COVID-19 vaccine hesitancy and predictor variables among diabetic patients. Hence, the study aimed to assess Covid-19 Vaccine Hesitancy and Predictor variables among Diabetic Patients on Follow-Up at Public Hospitals in Nekemte Town, Western Ethiopia.
Facility based cross sectional study was conducted among 422 diabetic patients attending public hospitals at Nekemte Town, Western Ethiopia between January, to February, 2023. Study participants were recruited by systematic random sampling. The data were collected interviewee administered pre-tested structured survey questioner. The collected data were entered and cleaned using Epi-Data software 4.6 version. The cleaned data were analyzed using SPSS. 25.0 Statical software. Descriptive statistics like frequency, mean and percentage, and binary logistic regression was applied to identify independent predictors of Covid-19 vaccine hesitancy and association between variables were declared at p-value of 0.05.
The overall magnitude of COVID-19 vaccine hesitancy was 15.2% (95% CI: 11.6-18.7). The top three listed reasons for the COVID-19 vaccine hesitancy were: negative information about the vaccine (32.90%), lack of enough information (21.80%), and vaccine safety concern (19.40%). The hesitancy of the COVID-19 vaccination uptake among diabetes patients was independently influenced by age between 40-49 (Adjusted Odd Ratio [AOR] = 4.52(1.04-19.66)), having vaccine awareness (AOR = 0.029(0.001-0.86)), having a great deal of trust on vaccine development (AOR = 0.028(0.002-0.52)), and a fear amount trust (AOR = 0.05(0.003-0.79)) on the vaccine preparation, vaccinated for COVID-19 (AOR = 0.13(0.04-0.51)), perceived exposure to COVID-19 infection after having the vaccine as strongly agree/agree (AOR = 0.03(0.01-0.17))and neither agree nor disagree (AOR = 0.07(0.02-0.30)).
COVID-19 vaccine hesitancy among diabetic patients was relatively low. The identified independent predictors were age, vaccine awareness, COVID-19 vaccination history, awareness on vaccine preparation and exposure status to COVID-19 infection. The relevant agency should focus on efforts to translating these high levels of vaccine acceptance into actual uptake, through targeting identifying predictor variables and vaccine availability for a high-risk diabetes patient.
了解和解决包括慢性病患者在内的疫苗犹豫者的担忧是提高疫苗接种率的关键。然而,在埃塞俄比亚,关于糖尿病患者对 COVID-19 疫苗的犹豫以及预测变量的证据有限。因此,本研究旨在评估在埃塞俄比亚西部内克姆特镇公立医院接受随访的糖尿病患者对 COVID-19 疫苗的犹豫情况和预测变量。
这是一项在 2023 年 1 月至 2 月期间在埃塞俄比亚西部内克姆特镇公立医院接受治疗的 422 名糖尿病患者中进行的基于设施的横断面研究。采用系统随机抽样的方法招募研究对象。通过预测试的结构化调查问卷对研究参与者进行访谈。使用 Epi-Data 软件 4.6 版收集和清理数据。使用 SPSS 25.0 统计软件对收集的数据进行分析。采用频率、均值和百分比等描述性统计方法,以及二元逻辑回归分析确定 COVID-19 疫苗犹豫的独立预测因素,并在 p 值为 0.05 时宣布变量之间的关联。
COVID-19 疫苗犹豫的总体程度为 15.2%(95%CI:11.6-18.7)。列出的 COVID-19 疫苗犹豫的前三个原因是:疫苗的负面信息(32.90%)、缺乏足够的信息(21.80%)和对疫苗安全性的担忧(19.40%)。糖尿病患者对 COVID-19 疫苗接种的犹豫程度受到年龄在 40-49 岁(调整后的优势比 [AOR] = 4.52(1.04-19.66))、疫苗意识(AOR = 0.029(0.001-0.86))、对疫苗开发的高度信任(AOR = 0.028(0.002-0.52))和对疫苗准备的恐惧(AOR = 0.05(0.003-0.79))的独立影响,接种过 COVID-19 疫苗(AOR = 0.13(0.04-0.51))、强烈同意/同意接种疫苗后接触 COVID-19 感染(AOR = 0.03(0.01-0.17))和既不同意也不反对(AOR = 0.07(0.02-0.30))的疫苗接种经历。
糖尿病患者对 COVID-19 疫苗的犹豫程度相对较低。确定的独立预测因素包括年龄、疫苗意识、COVID-19 疫苗接种史、疫苗准备意识和 COVID-19 感染接触状况。相关机构应通过针对确定的预测变量和高危糖尿病患者的疫苗供应,努力将这些高水平的疫苗接受度转化为实际接种率。