Sahile Addisu Tadesse, Gizaw Girma Demissie, Mgutshini Tennyson, Gebremariam Zewdu Minwuyelet, Bekele Getabalew Endazenaw
Department of Public Health, Unity University, Addis Ababa, Ethiopia.
Department of Public Health Emergency Management, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.
Can J Infect Dis Med Microbiol. 2022 Aug 25;2022:2313367. doi: 10.1155/2022/2313367. eCollection 2022.
The coronavirus disease 2019 pandemic has had a devastating impact on the everyday lives of the world's population and to this end, the development of curative vaccines was upheld as a welcome panacea. Despite the undeniable negative impact of the disease on human beings, lower than expected proportions of people have taken up the vaccines, particularly in the developing non-Western world. Ethiopia represents an interesting case example, of a nation where COVID-19 vaccine acceptance levels have not been well investigated and a need exists to assess the overall level of vaccine acceptance.
A systematic multidatabase search for relevant articles was carried out across Google Scholar, Web of Science, Science Direct, Hinari, EMBASE, Boolean operator, and PubMed. Two reviewers independently selected, reviewed, screened, and extracted data by using a Microsoft Excel spreadsheet. The Joanna Briggs Institute prevalence critical appraisal tools and the modified NewcastleOttawa Scale (NOS) were used to assess the quality of evidence. All studies conducted in Ethiopia, reporting vaccine acceptance rates were incorporated. The extracted data were imported into the comprehensive meta-analysis version 3.0 for further analysis. Heterogeneity was confirmed using Higgins's method, and publication bias was checked by using Beggs and Eggers tests. A random-effects meta-analysis model with a 95% confidence interval was computed to estimate the pooled prevalence. Furthermore, subgroup analysis based on the study area and sample size was done. . After reviewing 67 sources, 18 articles fulfilled the inclusion criteria and were included in the meta-analysis. The pooled prevalence of COVID-19 vaccine acceptance in Ethiopia was 57.8% (95% CI: 47.2%-67.8%). The level of COVID-19 vaccine acceptance in Ethiopia was at a lower rate than necessary to achieve herd immunity. The highest level of vaccine acceptance rate was reported via online or telephone surveys followed by the southern region of Ethiopia. The lowest vaccine acceptance patterns were reported in Addis Ababa.
2019年冠状病毒病疫情对全球人口的日常生活产生了毁灭性影响，为此，研发治疗性疫苗被视为一剂受欢迎的万灵药。尽管该疾病对人类有着不可否认的负面影响，但接种疫苗的人数比例低于预期，尤其是在非西方发展中世界。埃塞俄比亚是一个有趣的例子，该国的新冠疫苗接种接受程度尚未得到充分研究，因此有必要评估疫苗接种接受的总体水平。
通过谷歌学术、科学网、科学Direct、Hinari、EMBASE、布尔运算符和PubMed对相关文章进行系统的多数据库搜索。两名评审员使用Microsoft Excel电子表格独立选择、审查、筛选和提取数据。使用乔安娜·布里格斯研究所患病率批判性评估工具和改良的纽卡斯尔-渥太华量表（NOS）来评估证据质量。纳入所有在埃塞俄比亚进行的、报告疫苗接种率的研究。将提取的数据导入综合元分析版本3.0进行进一步分析。使用希金斯方法确认异质性，并使用贝格斯和埃格斯检验检查发表偏倚。计算具有95%置信区间的随机效应元分析模型以估计合并患病率。此外，还基于研究区域和样本量进行了亚组分析。在审查了67个来源后，18篇文章符合纳入标准并被纳入元分析。埃塞俄比亚新冠疫苗接种接受的合并患病率为57.8%（95%CI：47.2%-67.8%）。埃塞俄比亚的新冠疫苗接种接受水平低于实现群体免疫所需的水平。通过在线或电话调查报告的疫苗接种接受率最高，其次是埃塞俄比亚南部地区。亚的斯亚贝巴报告的疫苗接种接受模式最低。
