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外用锌预防复发性单纯疱疹感染:文献综述及建议方案

Use of topical zinc to prevent recurrent herpes simplex infection: review of literature and suggested protocols.

作者信息

Eby G A, Halcomb W W

出版信息

Med Hypotheses. 1985 Jun;17(2):157-65. doi: 10.1016/0306-9877(85)90142-2.

DOI:10.1016/0306-9877(85)90142-2
PMID:3897803
Abstract

Zinc ions have been reported to be antiviral to herpes simplex viruses. A number of treatments using zinc are reviewed which illustrate the effects of topically applied zinc in reducing the duration and severity of human orolabial and genital infections. Long-term topical application of zinc salts appears to greatly reduce or eliminate recurrences of genital herpetic infections.

摘要

据报道,锌离子对单纯疱疹病毒具有抗病毒作用。本文综述了多种使用锌的治疗方法,这些方法表明局部应用锌在减轻人类口腔和生殖器疱疹感染的持续时间和严重程度方面的效果。长期局部应用锌盐似乎能大大减少或消除生殖器疱疹感染的复发。

相似文献

1
Use of topical zinc to prevent recurrent herpes simplex infection: review of literature and suggested protocols.外用锌预防复发性单纯疱疹感染:文献综述及建议方案
Med Hypotheses. 1985 Jun;17(2):157-65. doi: 10.1016/0306-9877(85)90142-2.
2
Topical application of zinc-solutions: a new treatment for herpes simplex infections of the skin?
Acta Derm Venereol. 1980;60(2):175-77.
3
Topical treatment of recurrent herpes simplex and post-herpetic erythema multiforme with low concentrations of zinc sulphate solution.低浓度硫酸锌溶液局部治疗复发性单纯疱疹和疱疹后多形红斑。
Br J Dermatol. 1981 Feb;104(2):191-4. doi: 10.1111/j.1365-2133.1981.tb00044.x.
4
The diverse effects of topical and systemic administration of zinc on the virulence of herpes simplex genitalis.局部和全身应用锌对单纯疱疹性生殖器病致病力的不同影响。
Life Sci. 1979 May 14;24(20):1877-83. doi: 10.1016/0024-3205(79)90239-x.
5
Topical zinc in the treatment of mice infected intravaginally with herpes genitalis virus.局部应用锌治疗经阴道感染生殖器疱疹病毒的小鼠。
Proc Soc Exp Biol Med. 1980 Sep;164(4):593-7. doi: 10.3181/00379727-164-40922.
6
Failure of neutral-red photodynamic inactivation in recurrent herpes simplex virus infections.复发性单纯疱疹病毒感染中中性红光动力灭活失败
N Engl J Med. 1975 Nov 6;293(19):945-9. doi: 10.1056/NEJM197511062931901.
7
Acyclovir. A review of its pharmacodynamic properties and therapeutic efficacy.阿昔洛韦。对其药效学特性及治疗效果的综述。
Drugs. 1983 Nov;26(5):378-438. doi: 10.2165/00003495-198326050-00002.
8
Acyclovir for recurrent erythema multiforme caused by herpes simplex.阿昔洛韦用于治疗由单纯疱疹引起的复发性多形红斑。
J Am Acad Dermatol. 1988 Jan;18(1 Pt 2):197-9. doi: 10.1016/s0190-9622(88)70027-4.
9
Early clinical results show topical agent effective vs genital herpes.早期临床结果显示局部用药对生殖器疱疹有效。
Hosp Pract. 1979 Jan;14(1):44, 48, 53. doi: 10.1080/21548331.1979.11707465.
10
Topical zinc in the treatment of herpes simplex.
Cutis. 1986 Feb;37(2):130-1.

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A Comprehensive Overview of Epidemiology, Pathogenesis and the Management of Herpes Labialis.唇疱疹的流行病学、发病机制及治疗的全面概述。
Viruses. 2023 Jan 13;15(1):225. doi: 10.3390/v15010225.
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Comparative study of serum zinc concentration in recurrent herpes labialis patients and healthy individuals.复发性唇疱疹患者与健康个体血清锌浓度的比较研究。
BMC Oral Health. 2020 Oct 28;20(1):296. doi: 10.1186/s12903-020-01277-2.
3
Randomized, double-masked, placebo-controlled clinical study of the effectiveness of zinc acetate lozenges on common cold symptoms in allergy-tested subjects.
关于醋酸锌含片对经过过敏测试的受试者普通感冒症状疗效的随机、双盲、安慰剂对照临床研究。
Curr Ther Res Clin Exp. 1998 Sep;59(9):595-607. doi: 10.1016/S0011-393X(98)85058-3. Epub 2001 Oct 10.
4
Zinc lozenges as cure for the common cold--a review and hypothesis.锌含片治疗普通感冒——综述与假说。
Med Hypotheses. 2010 Mar;74(3):482-92. doi: 10.1016/j.mehy.2009.10.017. Epub 2009 Nov 10.
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Efficacy and toxicity of zinc salts as candidate topical microbicides against vaginal herpes simplex virus type 2 infection.锌盐作为候选局部用杀微生物剂抗阴道单纯疱疹病毒2型感染的疗效和毒性
Antimicrob Agents Chemother. 2005 Mar;49(3):1181-3. doi: 10.1128/AAC.49.3.1181-1183.2005.
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Zinc lozenges: cold cure or candy? Solution chemistry determinations.锌含片:是感冒药还是糖果?溶液化学测定
Biosci Rep. 2004 Feb;24(1):23-39. doi: 10.1023/b:bire.0000037754.71063.41.