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老年髋部骨折患者长期死亡率的预测因素。

Predictors of mortality over time in geriatric patients with hip fracture.

作者信息

Eversdijk Hubert A J, Nijdam Thomas M P, Kusen Jip Q, Schuijt Henk-Jan, Smeeing Diederik P J, van der Velde Detlef

机构信息

Department of Trauma Surgery, St. Antonius Ziekenhuis Utrecht, Utrecht, the Netherlands.

出版信息

OTA Int. 2024 Jul 8;7(3):e339. doi: 10.1097/OI9.0000000000000339. eCollection 2024 Sep.

Abstract

OBJECTIVES

The aim of this study was to determine the variations in effect for predictors of mortality over time and risk of in-hospital complications in geriatric patients with a hip fracture. Many studies have investigated risk factors of short-term and long-term mortality separately. In current literature, little is known about the variations in effect of risk factors over time and no comparison with the general population is made.

METHODS

All patients with a hip fracture aged 70 years or older admitted to our hospital between January 1, 2016, and May 1, 2018, were included in this retrospective study. Patients who had undergone total hip arthroplasty (THA) were not included. The primary outcome was mortality after 1 year. Secondary outcomes were mortality after 30 days, 90 days, 2 years, and complications. Kaplan-Meier (KM) curves for risk factors were generated to visualize survival over time. Data were compared with data extracted from the national health records.

RESULTS

A total of 685 geriatric patients with hip fractures were included with a 1-year mortality of 27%. The adjusted odds ratios (AOR) found differed over time. Five risk factors for mortality were investigated in this study using KM curves: age, prefracture living situation, dementia, sex, and ASA classification.

CONCLUSIONS

Over time, the variation of 5 risk factors for mortality were visualized in geriatric patients with a hip fracture: age, prefracture living situation, dementia, sex, and ASA classification. An elevated risk of mortality was discovered compared with the general population. The variation in effect observed in risk factors plays a vital role in prognosis. This insight will help guide accurate medical decision-making for a tailored treatment plan for geriatric patients with a hip fracture.

摘要

目的

本研究旨在确定老年髋部骨折患者死亡率预测因素的效应随时间的变化以及住院并发症风险。许多研究分别调查了短期和长期死亡率的危险因素。在当前文献中,关于危险因素效应随时间的变化知之甚少,且未与一般人群进行比较。

方法

本回顾性研究纳入了2016年1月1日至2018年5月1日期间我院收治的所有70岁及以上髋部骨折患者。接受全髋关节置换术(THA)的患者未纳入。主要结局是1年后的死亡率。次要结局是30天、90天、2年后的死亡率以及并发症。生成危险因素的Kaplan-Meier(KM)曲线以直观显示随时间的生存率。将数据与从国家健康记录中提取的数据进行比较。

结果

共纳入685例老年髋部骨折患者,1年死亡率为27%。发现调整后的比值比(AOR)随时间不同。本研究使用KM曲线调查了五个死亡危险因素:年龄、骨折前生活状况、痴呆、性别和美国麻醉医师协会(ASA)分级。

结论

随时间推移,在老年髋部骨折患者中可视化了五个死亡危险因素的变化:年龄、骨折前生活状况、痴呆、性别和ASA分级。与一般人群相比,发现死亡率风险升高。危险因素中观察到的效应变化在预后中起着至关重要的作用。这一见解将有助于指导为老年髋部骨折患者制定量身定制的治疗计划的准确医疗决策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28e0/11227347/7b60c6099f15/oi9-7-e339-g001.jpg

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