Nelius D
Z Gesamte Inn Med. 1975 Dec 15;30(24):274-5.
From own experiences the observations of 3 patients were reported who were immunosuppressively treated with purine antagonists (azathioprine and 6-mercaptopurine). Hereby in a severe allergic vasculitis in a 22-year-old patient and in a granulomatous arteritis during Wegener's granulomatosis in a 51-year-old patient remissions for more than 1 and 7 years, respectively, could be achieved under immunosuppressive long-term therapy. In the case of a periarteriitis nodosa death took place 2 months after administration of 6-mercaptopurine.
根据自身经验,报告了3例接受嘌呤拮抗剂(硫唑嘌呤和6-巯基嘌呤)免疫抑制治疗的患者的观察结果。在此,一名22岁患者患有严重过敏性血管炎,一名51岁患者在韦格纳肉芽肿病期间患有肉芽肿性动脉炎,分别在长期免疫抑制治疗下实现了超过1年和7年的缓解。在结节性多动脉炎的病例中,使用6-巯基嘌呤2个月后死亡。