Spritz R A
Pediatr Pathol. 1985;3(1):43-57. doi: 10.3109/15513818509068837.
Several rare disorders characterized by histiocytic hyperplasia are inherited as single-gene Mendelian traits. These familial forms of histiocytosis are heterogeneous and can be clearly distinguished from each other by clinical and genetic criteria. The genetic nature of these disorders can lead to familial recurrence and thus necessitates their distinction from the classical reticuloendothelioses. The clinical manifestations and modes of inheritance of the various familial histiocytoses are reviewed.
几种以组织细胞增生为特征的罕见疾病以单基因孟德尔性状遗传。这些组织细胞增多症的家族形式是异质性的，可以通过临床和遗传学标准清楚地相互区分。这些疾病的遗传性质可导致家族性复发，因此有必要将它们与经典的网状内皮组织增殖症区分开来。本文综述了各种家族性组织细胞增多症的临床表现和遗传方式。
