Harris L F
Postgrad Med. 1985 Sep 1;78(3):199-202. doi: 10.1080/00325481.1985.11699124.
Persons whose work or recreation exposes them to minor trauma out of doors are at risk for sporotrichosis. The disease is generally indolent, with the lymphocutaneous form being by far the commonest. Extracutaneous disease may affect the bones or joints, lungs, or other foci. Isolation of the fungus Sporothrix schenckii from involved tissue establishes the diagnosis. Saturated solution of potassium iodide is the first-line treatment of lymphocutaneous disease. Intravenous amphotericin B is used for lesions not responding to saturated solution of potassium iodide and, occasionally, excision of lesions is required. Amphotericin B also is the treatment of choice for extracutaneous sporotrichosis.
工作或娱乐时在户外遭受轻微创伤的人有患孢子丝菌病的风险。该病通常发展缓慢,其中皮肤淋巴管型最为常见。皮肤外疾病可能累及骨骼或关节、肺部或其他病灶。从受累组织中分离出申克孢子丝菌可确诊。碘化钾饱和溶液是皮肤淋巴管型疾病的一线治疗方法。静脉注射两性霉素B用于对碘化钾饱和溶液无反应的病灶,偶尔需要切除病灶。两性霉素B也是皮肤外孢子丝菌病的首选治疗药物。