Stevens D P
Rev Infect Dis. 1985 Jul-Aug;7(4):530-5. doi: 10.1093/clinids/7.4.530.
Giardia lamblia infects millions of individuals throughout the world. In developed countries it appears primarily in waterborne epidemics of diarrhea. In developing countries, it is endemic, but only a small proportion of those infected appear ill. This flagellate parasite infects the small intestine of its host and may cause malabsorption and malnutrition, particularly among infants and young children. Little is known about the extent of illness caused by this parasite because few epidemiologic studies have been done; diagnosis is difficult and Giardia carriers frequently are simultaneously infected with other pathogens. Control measures include intermittent treatment of those infected and improved water supply and sanitation. Efforts to control individual infection can only be successful on a temporary basis. The greatest progress in control should derive from efforts to develop an effective vaccine.
蓝氏贾第鞭毛虫感染着全球数百万人。在发达国家,它主要出现在水源性腹泻流行中。在发展中国家,它呈地方性流行,但只有一小部分感染者出现症状。这种鞭毛虫寄生虫感染宿主的小肠,可能导致吸收不良和营养不良,尤其是在婴幼儿中。由于很少进行流行病学研究,人们对这种寄生虫引起的疾病程度了解甚少;诊断困难,而且贾第虫携带者经常同时感染其他病原体。控制措施包括对感染者进行间歇性治疗以及改善供水和卫生条件。控制个体感染的努力只能暂时取得成功。控制方面的最大进展应来自于研发有效疫苗的努力。