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选择性初级卫生保健:发展中国家疾病控制策略。第十九部分。贾第虫病

Selective primary health care: strategies for control of disease in the developing world. XIX. Giardiasis.

作者信息

Stevens D P

出版信息

Rev Infect Dis. 1985 Jul-Aug;7(4):530-5. doi: 10.1093/clinids/7.4.530.

DOI:10.1093/clinids/7.4.530
PMID:3898310
Abstract

Giardia lamblia infects millions of individuals throughout the world. In developed countries it appears primarily in waterborne epidemics of diarrhea. In developing countries, it is endemic, but only a small proportion of those infected appear ill. This flagellate parasite infects the small intestine of its host and may cause malabsorption and malnutrition, particularly among infants and young children. Little is known about the extent of illness caused by this parasite because few epidemiologic studies have been done; diagnosis is difficult and Giardia carriers frequently are simultaneously infected with other pathogens. Control measures include intermittent treatment of those infected and improved water supply and sanitation. Efforts to control individual infection can only be successful on a temporary basis. The greatest progress in control should derive from efforts to develop an effective vaccine.

摘要

蓝氏贾第鞭毛虫感染着全球数百万人。在发达国家,它主要出现在水源性腹泻流行中。在发展中国家,它呈地方性流行,但只有一小部分感染者出现症状。这种鞭毛虫寄生虫感染宿主的小肠,可能导致吸收不良和营养不良,尤其是在婴幼儿中。由于很少进行流行病学研究,人们对这种寄生虫引起的疾病程度了解甚少;诊断困难,而且贾第虫携带者经常同时感染其他病原体。控制措施包括对感染者进行间歇性治疗以及改善供水和卫生条件。控制个体感染的努力只能暂时取得成功。控制方面的最大进展应来自于研发有效疫苗的努力。

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1
Selective primary health care: strategies for control of disease in the developing world. XIX. Giardiasis.选择性初级卫生保健:发展中国家疾病控制策略。第十九部分。贾第虫病
Rev Infect Dis. 1985 Jul-Aug;7(4):530-5. doi: 10.1093/clinids/7.4.530.
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Giardiasis. Issues in diagnosis and management.贾第虫病。诊断与管理中的问题。
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Giardiasis: a common and underrecognized enteric pathogen.
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Management of giardiasis.贾第虫病的管理
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Giardiasis: An Overview.贾第虫病概述
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Giardiasis: a common cause of diarrheal disease.
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Rapid reinfection by Giardia lamblia after treatment in a hyperendemic Third World community.在一个高度流行的第三世界社区中,贾第虫治疗后快速再次感染。
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[A therapeutic trial in Giardia muris infection in the mouse with metronidazole, tinidazole, secnidazole and furazolidone].[甲硝唑、替硝唑、塞克硝唑和呋喃唑酮对小鼠鼠贾第虫感染的治疗试验]
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引用本文的文献

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The relationship of water sources and other determinants to prevalence of intestinal protozoal infections in a rural community of Saudi Arabia.沙特阿拉伯一个农村社区的水源及其他决定因素与肠道原生动物感染患病率的关系。
J Community Health. 1995 Oct;20(5):433-40. doi: 10.1007/BF02260439.
2
Parasitic infections of the small intestine.小肠寄生虫感染
Gut. 1994 Mar;35(3):289-93. doi: 10.1136/gut.35.3.289.
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Giardia lamblia in children and the child care setting: a review of the literature.儿童及儿童保育环境中的蓝氏贾第鞭毛虫:文献综述
J Paediatr Child Health. 1994 Jun;30(3):202-9. doi: 10.1111/j.1440-1754.1994.tb00620.x.
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Unusual ribosomal RNA of the intestinal parasite Giardia lamblia.肠道寄生虫蓝氏贾第鞭毛虫的异常核糖体RNA。
Nucleic Acids Res. 1987 Oct 12;15(19):7889-901. doi: 10.1093/nar/15.19.7889.
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From Leningrad to the day-care center. The ubiquitous Giardia lamblia.从列宁格勒到日托中心。无处不在的蓝氏贾第鞭毛虫。
West J Med. 1990 Aug;153(2):154-9.
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Detection of Giardia cysts with a cDNA probe and applications to water samples.
Appl Environ Microbiol. 1991 Apr;57(4):927-31. doi: 10.1128/aem.57.4.927-931.1991.
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Giardia--diagnosis, clinical course and epidemiology. A review.贾第虫——诊断、临床病程及流行病学。综述。
Epidemiol Infect. 1992 Aug;109(1):1-22.