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晚年参与社会活动增加与老年人全因死亡率和心脏病风险的关系:来自中国长寿纵向研究(CLHLS)的结果。

Association of increased participation in social activity in later life with risk of all-cause mortality and heart diseases in older people: results from the Chinese Longitudinal Healthy Longevity Survey (CLHLS).

机构信息

Department of Cardiology, West China Hospital of Sichuan University, Chengdu, China.

Department of Cardiology, Hospital of Traditional Chinese Medicine, Chengdu, China.

出版信息

Front Public Health. 2024 Jun 25;12:1396184. doi: 10.3389/fpubh.2024.1396184. eCollection 2024.

Abstract

BACKGROUND

Previous studies have shown social activity is associated with reduced risk of health outcomes. However, among older people (≥65 years) who were socially inactive at baseline, limited study explored whether increased participation in social activity in later life was associated with reduced risk of health outcomes; therefore, using the data from the Chinese Longitudinal Healthy Longevity Survey, the study was performed.

METHODS

The study outcomes were 10-year all-cause mortality (sample number = 9,984) and 10-year heart diseases (sample number = 7,496). The exposure was the change of social activity frequency. Cox regression analysis was used for data analysis.

RESULTS

During the follow-up, there were 6,407 all-cause mortalities and 1,035 heart diseases, respectively. Kaplan-Meier analysis demonstrated that cumulative incidences of all-cause mortality were significantly lower in participants with changes into more frequent social activity (log-rank  < 0.001), while no significant difference was observed for heart diseases (log-rank  = 0.330). Compared with the subgroup who never participated in social activity at baseline, adjusted HRs of all-cause mortality were 0.79 (95% CI: 0.70-0.90,  < 0.001), 0.78 (95% CI: 0.63-0.96,  = 0.019), 0.74 (0.59-0.92,  = 0.006), and 0.70 (95% CI: 0.56-0.88,  = 0.002) for the subgroup of switching to sometimes, the subgroup of switching to once a month, the subgroup of switching to once a week, and the subgroup of switching to everyday, respectively. The corresponding HRs of heart diseases were 0.83 (95% CI: 0.65-1.08,  = 0.170), 0.82 (95% CI: 0.51-1.31,  = 0.412), 0.91 (0.58-1.42,  = 0.675) and 0.75 (95% CI: 0.47-1.20,  = 0.227), respectively. Stratified and sensitivity analyses revealed similar results.

CONCLUSION

Among older people who never participated in social activity, increased participation in social activity in later life was associated with reduced risk of all-cause mortality, but was not associated with reduced risk of heart diseases.

摘要

背景

先前的研究表明,社交活动与健康结果风险降低有关。然而,在基线时社交不活跃的老年人(≥65 岁)中,很少有研究探讨晚年增加社交活动的参与是否与健康结果风险降低有关;因此,本研究使用了中国长寿纵向研究的数据。

方法

本研究的结局是 10 年全因死亡率(样本量=9984)和 10 年心脏病(样本量=7496)。暴露因素是社交活动频率的变化。采用 Cox 回归分析进行数据分析。

结果

在随访期间,分别有 6407 例全因死亡和 1035 例心脏病。Kaplan-Meier 分析表明,在更频繁地参加社交活动的参与者中,全因死亡率的累积发生率明显较低(对数秩检验<0.001),而心脏病则没有显著差异(对数秩检验=0.330)。与基线时从未参加过社交活动的亚组相比,全因死亡率的调整 HR 分别为 0.79(95%CI:0.70-0.90,<0.001)、0.78(95%CI:0.63-0.96,=0.019)、0.74(0.59-0.92,=0.006)和 0.70(95%CI:0.56-0.88,=0.002),分别为从不参加社交活动亚组切换到有时参加、每月参加一次亚组、每周参加一次亚组和每天参加一次亚组。相应的心脏病 HR 分别为 0.83(95%CI:0.65-1.08,=0.170)、0.82(95%CI:0.51-1.31,=0.412)、0.91(0.58-1.42,=0.675)和 0.75(95%CI:0.47-1.20,=0.227),分别为从不参加社交活动亚组切换到有时参加、每月参加一次亚组、每周参加一次亚组和每天参加一次亚组。分层和敏感性分析显示出相似的结果。

结论

在从未参加过社交活动的老年人中,晚年增加社交活动的参与与全因死亡率降低有关,但与心脏病发病率降低无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d301/11231370/9b399e03efde/fpubh-12-1396184-g001.jpg

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