Suppr超能文献

长期饮用天然水与降低老年人全因死亡率相关:来自中国的纵向前瞻性研究。

Drinking natural water unchangeably is associated with reduced all-cause mortality in elderly people: A longitudinal prospective study from China.

机构信息

Department of Cardiology, West China Hospital of Sichuan University, Chengdu, China.

Department of Cardiology, Hospital of Traditional Chinese Medicine of Shuangliu District, Chengdu, China.

出版信息

Front Public Health. 2022 Aug 22;10:981782. doi: 10.3389/fpubh.2022.981782. eCollection 2022.

Abstract

OBJECTIVE

Because of rapid economic growth and followed urban expansion in China, many people drinking natural water had to change their water sources to tap water. We aimed to test the unknown association that whether continued use of natural water for drinking is different from switching to tap water in all-cause mortality risks in elderly people.

METHODS

In total, based on Chinese Longitudinal Healthy Longevity Survey, 26,688 elderly participants drinking natural water from childhood to young-old were included in the final analyses. Associations between whether changing drinking water sources or not and all-cause mortality risk were then estimated by Cox regression models with the use of multiple propensity score methods, and the primary analysis used propensity score matching, with other propensity score methods confirming the robustness of the results.

RESULTS

Baseline characteristics were fairly well balanced by the three post-randomization methods. During a median follow-up period of 3.00 (IQR: 1.52, 5.73) years, 21,379 deaths were recorded. The primary analysis showed people using natural water unchangeably was associated with a lower risk of all-cause mortality than those switching to tap water in later life (HR: 0.94, 95% CI: 0.91-0.97, < 0.001). Other propensity score methods, as well as Cox regression analysis without using propensity score methods, showed similar results.

CONCLUSIONS

Among elderly people depending on natural water for drinking from their childhood to young-old in China, continued use of natural water was associated with a lower all-cause mortality risk than conversion to tap water later. Further studies in different countries and populations are needed to verify our conclusions.

摘要

目的

由于中国经济的快速增长和随之而来的城市扩张,许多饮用自然水的人不得不改变水源,转而使用自来水。我们旨在检验一个未知的关联,即对于老年人而言,持续饮用自然水与切换到自来水在全因死亡率风险方面是否存在差异。

方法

基于中国长寿纵向研究,我们共纳入了 26688 名从儿童期到老年期一直饮用自然水的老年参与者进行最终分析。然后,我们采用 Cox 回归模型和多种倾向评分方法来估计是否改变饮水水源与全因死亡率风险之间的关联,并采用倾向评分匹配进行主要分析,其他倾向评分方法则确认了结果的稳健性。

结果

通过三种后随机化方法,基线特征得到了很好的平衡。在中位数为 3.00(IQR:1.52,5.73)年的随访期间,记录到 21379 例死亡。主要分析显示,与后来改用自来水的人群相比,一直饮用自然水的人群全因死亡率风险较低(HR:0.94,95%CI:0.91-0.97,<0.001)。其他倾向评分方法以及未使用倾向评分方法的 Cox 回归分析也显示出了相似的结果。

结论

在中国,从儿童期到老年期一直依赖自然水作为饮用水的老年人中,与改用自来水相比,持续饮用自然水与全因死亡率风险降低相关。需要在不同国家和人群中开展进一步的研究来验证我们的结论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc36/9441631/e01f8be7f625/fpubh-10-981782-g0001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验