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结直肠癌的开放手术方式真的变得不常见了吗?

Has the open surgical approach in colorectal cancer really become uncommon?

作者信息

Cariati Maria, Brisinda Giuseppe, Chiarello Maria Michela

机构信息

Department of Surgery, Azienda Sanitaria Provinciale di Crotone, Crotone 88900, Italy.

Abdominal and Endocrine Metabolic Medical and Surgical Sciences, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome 00168, Italy.

出版信息

World J Gastrointest Surg. 2024 Jun 27;16(6):1485-1492. doi: 10.4240/wjgs.v16.i6.1485.

Abstract

Colorectal cancer is the third most common cancer in the world. Surgery is mandatory to treat patients with colorectal cancer. Can colorectal cancer be treated in laparoscopy? Scientific literature has validated the oncological quality of laparoscopic approach for the treatment of patients with colorectal cancer. Randomized non-inferiority trials with good remote control have answered positively to this long-debated question. Early as 1994, first publications demonstrated technical feasibility and compliance with oncological imperatives and, as far as short-term outcomes are concerned, there is no difference in terms of mortality and post-operative morbidity between open and minimally invasive surgical approaches, but only longer operating times at the beginning of the experience. Subsequently, from 2007 onwards, long-term results were published that demonstrated the absence of a significant difference regarding overall survival, disease-free survival, quality of life, local and distant recurrence rates between open and minimally invasive surgery. In this editorial, we aim to summarize the clinical and technical aspects which, even today, make the use of open surgery relevant and necessary in the treatment of patients with colorectal cancer.

摘要

结直肠癌是全球第三大常见癌症。手术是治疗结直肠癌患者的必要手段。结直肠癌可以通过腹腔镜手术治疗吗?科学文献已经证实了腹腔镜手术治疗结直肠癌患者的肿瘤学质量。具有良好远期疗效的随机非劣效性试验对这个长期存在争议的问题给出了肯定的答案。早在1994年,首批出版物就证明了其技术可行性以及符合肿瘤学要求,就短期疗效而言,开放手术和微创手术在死亡率和术后发病率方面没有差异,但在经验积累初期,微创手术的手术时间更长。随后,从2007年起,有长期结果发表,表明开放手术和微创手术在总生存率、无病生存率、生活质量、局部和远处复发率方面没有显著差异。在这篇社论中,我们旨在总结即使在今天,开放手术在结直肠癌患者治疗中仍然相关且必要的临床和技术方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8830/11230011/fb5faf44178a/WJGS-16-1485-g001.jpg

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