Shen XingXing, Wang Shuai, Chen Jiahao, Li Junyi, Li Congcong, Xiang Ruian, Zhao Chuanxi, Xu Xuemeng
The Fifth Clinical Medical School, Guangzhou University of Chinese Medicine, Guangzhou, China.
Guangdong Second Traditional Chinese Medicine Hospital, Guangzhou, China.
Front Bioeng Biotechnol. 2024 Jun 21;12:1385986. doi: 10.3389/fbioe.2024.1385986. eCollection 2024.
The study enrolled a total of 80 lower legs of 40 participants (all female) with unilateral or bilateral KOA, who were assessed by two raters at three different time points. The inter-rater and test-retest reliability of the FPI-6 was evaluated using the intra-class correlation coefficient (ICC), while the absolute reliability of FPI-6 was examined using the standard error of measurement (SEM), minimum detectable change (MDC), and Bland-Altman analysis. The internal consistency of FPI-6 was assessed using Spearman's correlation coefficient. Additionally, MyotonPRO was employed to assess quadriceps muscle tone and stiffness in all participants, and the association between quadriceps muscle tone/stiffness and the total score of FPI-6 was analyzed.
Our study found excellent inter-rater and test-retest reliability (ICC values of 0.923 and 0.931, respectively) for the FPI-6 total score, as well as good to excellent reliability (ICC values ranging from 0.680 to 0.863 and 0.739-0.883) for individual items. The SEM and MDC values for the total score of FPI-6 among our study inter-rater were 0.78 and 2.15, respectively. and the SEM and MDC values for the test-retest total score of FPI-6 were found to be 0.76 and 2.11, respectively. Furthermore, the SEM and MDC values between inter-rater and test-retest across six individual items ranged from 0.30 to 0.56 and from 0.84 to 1.56. The Bland-Altman plots and respective 95% LOA showed no evidence of systematic bias. In terms of the mechanical properties of the quadriceps on both sides, the muscle tone and stiffness of rectus femoris (RF), vastus medialis (VM), and vastus lateralis (VL) were significantly higher in the non-dominant leg compared to the dominant leg. Additionally, in the non-dominant leg, there was a significant positive correlation between the muscle tone and stiffness of VM, VL, RF and the total score of FPI-6. However, in the dominant leg, only VM's muscle tone and stiffness showed a significant positive correlation with the total score of FPI-6.
The reliability of the FPI-6 total score and its six individual items was good to excellent. Our findings offer a straightforward and dependable approach for researchers to assess foot posture in elderly female patients with KOA. Furthermore, we observed significantly greater quadriceps tension and stiffness in the non-dominant leg compared to the dominant leg. The FPI-6 total score exhibited a significant correlation with changes in quadriceps muscle performance among KOA patients. These observations regarding the relationship between changes in quadriceps muscle performance and foot posture in elderly female KOA patients may provide novel insights for disease prevention, treatment, and rehabilitation.
本研究共纳入40例单侧或双侧KOA患者(均为女性)的80条小腿,由两名评估者在三个不同时间点进行评估。使用组内相关系数(ICC)评估FPI-6的评分者间信度和重测信度,同时使用测量标准误(SEM)、最小可检测变化(MDC)和Bland-Altman分析检查FPI-6的绝对信度。使用Spearman相关系数评估FPI-6的内部一致性。此外,使用MyotonPRO评估所有参与者的股四头肌肌张力和刚度,并分析股四头肌肌张力/刚度与FPI-6总分之间的关联。
我们的研究发现FPI-6总分具有出色的评分者间信度和重测信度(ICC值分别为0.923和0.931),各单项的信度良好至出色(ICC值范围为0.680至0.863和0.739 - 0.883)。我们研究中评分者间FPI-6总分的SEM和MDC值分别为0.78和2.15,FPI-6重测总分的SEM和MDC值分别为0.76和2.11。此外,六个单项评分者间和重测间的SEM和MDC值范围为0.30至0.56和0.84至1.56。Bland-Altman图及各自的95%一致性界限未显示出系统偏差的证据。在双侧股四头肌的力学特性方面,非优势侧股直肌(RF)、股内侧肌(VM)和股外侧肌(VL)的肌张力和刚度显著高于优势侧。此外,在非优势侧,VM、VL、RF的肌张力和刚度与FPI-6总分之间存在显著正相关。然而,在优势侧,仅VM的肌张力和刚度与FPI-6总分存在显著正相关。
FPI-6总分及其六个单项的信度良好至出色。我们的研究结果为研究人员评估老年女性KOA患者的足部姿势提供了一种直接且可靠的方法。此外,我们观察到非优势侧股四头肌的张力和刚度明显高于优势侧。FPI-6总分与KOA患者股四头肌肌肉性能变化显著相关。这些关于老年女性KOA患者股四头肌肌肉性能变化与足部姿势关系的观察结果可能为疾病的预防、治疗和康复提供新的见解。